Cardiovasc. Pathol.
Comparative pathology of human and canine myxomatous mitral valve degeneration: 5HT and TGF-ß mechanisms.
Oyama MA, Elliott C, Loughran KA, Kossar AP, Castillero E, Levy RJ, Ferrari G
Myxomatous mitral valve degeneration (MMVD) is a leading cause of valve repair or replacement secondary to the production of mitral regurgitation, car ...
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Source: PubMed
Multimed Man Cardiothorac Surg
How to create patient-specific loops for correcting mitral valve prolapse through a minimally invasive approach.
Fortunato G, Battellini R, Raffaelli P, Kotowicz V
A 72-year-old woman with a 6-month history of severe mitral valve regurgitation presented at our institution with dyspnea (NYHA II-III) and left ventr ...
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Source: PubMed
Eur J Med Genet 2020 Jan 23
A single nucleotide deletion resulting in a frameshift in exon 4 of TAB2 is associated with a polyvalular syndrome.
Permanyer E, Laurie S, Blasco-Lucas A, Maldonado G, Amador-Catalan A, Ferrer-Curriu G, Fuste B, Perez ML, Gonzalez-Alujas T, Beltran S, Comas-Riu J, Bardají A, Evangelista A, Galiñanes M
Polyvalvularmyxomatous degeneration is a rare clinical condition. A 51-year-old male patient presented at our centre with all four heart valves with m ...
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Source: PubMed
BMC Cardiovasc Disord
A novel TAB2 nonsense mutation (p.S149X) causing autosomal dominant congenital heart defects: a case report of a Chinese family.
Chen J, Yuan H, Xie K, Wang X, Tan L, Zou Y, Yang Y, Pan L, Xiao J, Chen G, Liu Y
TAB2 is an activator of MAP 3?K7/TAK1, which is required for the IL-1 induced signal pathway. Microdeletions encompassing TAB2 have been detected in v ...
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Source: PubMed
