Dis Model Mech 2020 Jan 31
Inactivation of Zeb1 in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure.
Carpinelli MR, de Vries ME, Auden A, Butt T, Deng Z, Partridge DD, Miles LB, Georgy SR, Haigh JJ, Darido C, Brabletz S, Brabletz T, Stemmler MP, Dworkin S, Jane SM
Cleft lip and palate are common birth defects resulting from failure of the facial processes to fuse during development. The mammalian grainyhead-like ...
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Source: PubMed
Ther Drug Monit 2020 Jan 29
Therapeutic drug monitoring of HIV antiretroviral drugs in pregnancy: A narrative review.
O'Kelly B, Murtagh Ba R, Lambert JS
To date, therapeutic drug monitoring (TDM) has played an important role in the management of pregnant HIV patients on highly active antiretroviral the ...
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Source: PubMed
EMBO Mol Med 2020 Jan 31
Inhibiting MARSs reduces hyperhomocysteinemia-associated neural tube and congenital heart defects.
Mei X, Qi D, Zhang T, Zhao Y, Jin L, Hou J, Wang J, Lin Y, Xue Y, Zhu P, Liu Z, Huang L, Nie J, Si W, Ma J, Ye J, Finnell RH, Saiyin H, Wang H, Zhao J, Zhao S, Xu W
Hyperhomocysteinemia is a common metabolic disorder that imposes major adverse health consequences. Reducing homocysteine levels, however, is not alwa ...
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Source: PubMed
J Obstet Gynaecol 2020 Jan 30
Reproductive health issues in female patients with beta-thalassaemia major: a narrative literature review.
Nourollahpour Shiadeh M, Cassinerio E, Modarres M, Zareiyan A, Hamzehgardeshi Z, Behboodi Moghadam Z
ß-thalassaemia major (BTM) has a high prevalence worldwide and is associated with considerable morbidity and mortality. The aim of this review is to p ...
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Source: PubMed
Biom J 2020 Jan 29
Bayesian latent class models for capture-recapture in the presence of missing data.
Di Cecco D, Di Zio M, Liseo B
We propose a method for estimating the size of a population in a multiple record system in the presence of missing data. The method is based on a late ...
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Source: PubMed
