Nutrition
Association between Low Muscle Mass and Survival in Incurable Cancer Patients: A Systematic Review.
Wiegert EVM, de Oliveira LC, Calixto-Lima L, Borges NA, Rodrigues J, da Mota E Silva Lopes MS, Peres WAF
Current data suggest that low skeletal muscle mass provides prognostic information in patients with cancer and may even be considered a biomarker in r ...
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Source: PubMed
Eur J Med Chem
Imidazo[2,1-b] [1,3,4]thiadiazoles with antiproliferative activity against primary and gemcitabine-resistant pancreatic cancer cells.
Cascioferro S, Petri GL, Parrino B, Carbone D, Funel N, Bergonzini C, Mantini G, Dekker H, Geerke D, Peters GJ, Cirrincione G, Giovannetti E, Diana P
A new series of eighteen imidazo [2,1-b] [1,3,4]thiadiazole derivatives was efficiently synthesized and screened for antiproliferative activity agains ...
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Source: PubMed
Pancreatology 2020 Jan 20
Characterization of CEL-DUP2: Complete duplication of the carboxyl ester lipase gene is unlikely to influence risk of chronic pancreatitis.
Fjeld K, Masson E, Lin JH, Michl P, Stokowy T, Gravdal A, El Jellas K, Steine SJ, Hoem D, Johansson BB, Dalva M, Ruffert C, Zou WB, Li ZS, Njølstad PR, Chen JM, Liao Z, Johansson S, Rosendahl J, Férec C, Molven A
Carboxyl ester lipase is a pancreatic enzyme encoded by CEL, an extremely polymorphic human gene. Pathogenic variants of CEL either increases the risk ...
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Source: PubMed
Pancreatology 2020 Jan 22
CD109 promotes the tumorigenic ability and metastatic motility of pancreatic ductal adenocarcinoma cells.
Hatsuzawa Y, Yamaguchi K, Takanashi T, Sato I, Tamai K, Mochizuki M, Iwai W, Wakui Y, Abue M, Yamamoto K, Yasuda J, Mizuma M, Unno M, Sugamura K
Accumulating evidence indicates that CD109, a glycosylphosphatidylinositol-anchored glycoprotein, is highly expressed in human epithelial carcinomas o ...
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Source: PubMed
Clin Nutr 2020 Jan 22
Automated body composition analysis of clinically acquired computed tomography scans using neural networks.
Paris MT, Tandon P, Heyland DK, Furberg H, Premji T, Low G, Mourtzakis M
The quantity and quality of skeletal muscle and adipose tissue is an important prognostic factor for clinical outcomes across several illnesses. Clini ...
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Source: PubMed