J Huntingtons Dis 2020 Jan 28
Transcriptional Assessment of Striatal mRNAs as Valid Biomarkers of Disease Progression in Three Mouse Models of Huntington's Disease.
Ghavami A, Olsen M, Kwan M, Beltran J, Shea J, Ramboz S, Duan W, Lavery D, Howland D, Park LC
Huntington's disease (HD) is a progressive neurodegenerative disorder that prominently affects the basal ganglia, leading to affective, cognitive, beh ...
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Source: PubMed
Life Sci. 2020 Jan 29
Targeted lipidomics and transcriptomics profiling reveal the heterogeneity of visceral and subcutaneous white adipose tissue.
Hou B, Zhao Y, He P, Xu C, Ma P, Lam SM, Li B, Gil V, Shui G, Qiang G, Liew CW, Du G
The depot-specific differences in lipidome of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) reflect heterogeneity of white adipo ...
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Source: PubMed
Endocrine 2020 Jan 31
Impact of acute-phase insulin secretion on glycemic variability in insulin-treated patients with type 2 diabetes.
Si Y, Shen Y, Lu J, Ma X, Zhang L, Mo Y, Lu W, Zhu W, Bao Y, Hu G, Zhou J
The association between ß-cell function and glycemic variability remains to be clarified in insulin-treated patients with type 2 diabetes. Therefore, ...
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Source: PubMed
Sci Rep
Practical application of short-term intensive insulin therapy based on the concept of "treat to target" to reduce hypoglycaemia in routine clinical site.
Nakashima K, Okamura N, Sanefuji H, Kaneto H
The aim is to devise a new short-term intensive insulin therapy (N-SIIT) based on the concept of "treat to target" to avoid hypoglycaemia and was appl ...
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Source: PubMed
Neurogastroenterol. Motil. 2020 Jan 31
Ephrin-B2 signaling in the spinal cord as a player in post-inflammatory and stress-induced visceral hypersensitivity.
Theofanous SA, Florens MV, Appeltans I, Denadai Souza A, Wood JN, Wouters MM, Boeckxstaens GE
Ephrin-B2/EphB receptor signaling contributes to persistent pain states such as postinflammatory and neuropathic pain. Visceral hypersensitivity (VHS) ...
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Source: PubMed
