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Latest Publications and Research on Statins

Heart Fail Rev   2020 Feb 01   

Effects of statins on the biological features of mesenchymal stem cells and therapeutic implications.

Gorabi AM, Kiaie N, Pirro M, Bianconi V, Jamialahmadi T, Sahebkar A

Statins are well-known lipid-lowering drugs. The pleiotropic effects of statins have brought about some beneficial effects on improving the therapeuti ... Read More

Source: PubMed
Biochim Biophys Acta Rev Cancer      

Cholesterol and beyond - The role of the mevalonate pathway in cancer biology.

Göbel A, Rauner M, Hofbauer LC, Rachner TD

Cancer is a multifaceted global disease. Transformation of a normal to a malignant cell takes several steps, including somatic mutations, epigenetic a ... Read More

Source: PubMed
Ageing Res. Rev.      

Effects of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on ageing: Molecular mechanisms.

Bahrami A, Bo S, Jamialahmadi T, Sahebkar A

Human ageing is determined by degenerative alterations and processes with different manifestations such as gradual organ dysfunction, tissue function ... Read More

Source: PubMed
Eur J Health Econ   2020 Feb 01   

Patients with coronary artery disease after acute myocardial infarction: effects of continuous enrollment in a structured Disease Management Program on adherence to guideline-recommended medication, health care expenditures, and survival.

Kirsch F, Becker C, Schramm A, Maier W, Leidl R

Acute myocardial infarction (AMI) carries increased risk of mortality and excess costs. Disease Management Programs (DMPs) providing guideline-recomme ... Read More

Source: PubMed
Dis Model Mech   2020 Jan 31   

Familial hypercholesterolemia class II low density lipoprotein-receptor response to statin treatment.

Omer L, Hindi L, Militello G, Stivers KB, Tien KC, Boyd NL

LDL receptor (LDLR) mutations are the primary cause of familial hypercholesterolemia (FH). Class II LDLR mutations result in a misfolded LDLR retained ... Read More

Source: PubMed

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