Heart Fail Rev 2020 Feb 01
Effects of statins on the biological features of mesenchymal stem cells and therapeutic implications.
Gorabi AM, Kiaie N, Pirro M, Bianconi V, Jamialahmadi T, Sahebkar A
Statins are well-known lipid-lowering drugs. The pleiotropic effects of statins have brought about some beneficial effects on improving the therapeuti ...
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Source: PubMed
Biochim Biophys Acta Rev Cancer
Cholesterol and beyond - The role of the mevalonate pathway in cancer biology.
Göbel A, Rauner M, Hofbauer LC, Rachner TD
Cancer is a multifaceted global disease. Transformation of a normal to a malignant cell takes several steps, including somatic mutations, epigenetic a ...
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Source: PubMed
Ageing Res. Rev.
Effects of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on ageing: Molecular mechanisms.
Bahrami A, Bo S, Jamialahmadi T, Sahebkar A
Human ageing is determined by degenerative alterations and processes with different manifestations such as gradual organ dysfunction, tissue function ...
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Source: PubMed
Eur J Health Econ 2020 Feb 01
Patients with coronary artery disease after acute myocardial infarction: effects of continuous enrollment in a structured Disease Management Program on adherence to guideline-recommended medication, health care expenditures, and survival.
Kirsch F, Becker C, Schramm A, Maier W, Leidl R
Acute myocardial infarction (AMI) carries increased risk of mortality and excess costs. Disease Management Programs (DMPs) providing guideline-recomme ...
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Source: PubMed
Dis Model Mech 2020 Jan 31
Familial hypercholesterolemia class II low density lipoprotein-receptor response to statin treatment.
Omer L, Hindi L, Militello G, Stivers KB, Tien KC, Boyd NL
LDL receptor (LDLR) mutations are the primary cause of familial hypercholesterolemia (FH). Class II LDLR mutations result in a misfolded LDLR retained ...
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Source: PubMed
