Biochem. Genet. 2020 Feb 01
WBSCR22 Competes with Long Non-coding RNA Linc00346 for miR-509-5p Binding Site to Regulate Cancer Stem Cell Phenotypes of Colorectal Cancer.
Zhao H, Su W, Sun Y, Wu Z
Various Long non-coding RNAs (lncRNAs) and MicroRNAs (miRNAs) have been demonstrated to be involved in colorectal cancer stem cells (CSCs). WBSCR22 is ...
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Source: PubMed
Tissue Eng Regen Med 2020 Feb 01
Primary Cilia Mediate Wnt5a/ß-catenin Signaling to Regulate Adipogenic Differentiation of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Following Calcium Induction.
Bae YK, Kim GH, Kwon JH, Kim M, Choi SJ, Oh W, Um S, Jin HJ
Regeneration of soft tissue defects is essential for adipose tissue pathologies and disease, trauma, or injury-induced damage. Here, we show that umbi ...
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Source: PubMed
Stem Cell Rev Rep 2020 Feb 01
Characterization of an Anti-CD5 Directed CAR T-Cell against T-Cell Malignancies.
Wada M, Zhang H, Fang L, Feng J, Tse CO, Zhang W, Chen Q, Sha S, Cao Y, Chen KH, Pinz KG, Chen X, Fan XX, Jiang X, Ma Y
T-cell malignancies often result in poor prognosis and outcome for patients. Immunotherapy has recently emerged as a revolutionary treatment against c ...
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Source: PubMed
Heart Fail Rev 2020 Feb 01
Effects of statins on the biological features of mesenchymal stem cells and therapeutic implications.
Gorabi AM, Kiaie N, Pirro M, Bianconi V, Jamialahmadi T, Sahebkar A
Statins are well-known lipid-lowering drugs. The pleiotropic effects of statins have brought about some beneficial effects on improving the therapeuti ...
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Source: PubMed
J. Clin. Immunol. 2020 Feb 01
Human BCL10 Deficiency due to Homozygosity for a Rare Allele.
Van Den Rym A, Taur P, Martinez-Barricarte R, Lorenzo L, Puel A, Gonzalez-Navarro P, Pandrowala A, Gowri V, Safa A, Toledano V, Cubillos-Zapata C, López-Collazo E, Vela M, Pérez-Martínez A, Sánchez-Ramón S, Recio MJ, Casanova JL, Desai MM, Perez de Diego R
In 2014, a child with broad combined immunodeficiency (CID) who was homozygous for a private BCL10 allele was reported to have complete inherited huma ...
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Source: PubMed
