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Latest Publications and Research on Telomere Shortening And Ageing

Sci. Total Environ.      

Early life tobacco exposure and children's telomere length: The HELIX project.

Osorio-Yáñez C, Clemente DBP, Maitre L, Vives-Usano M, Bustamante M, Martinez D, Casas M, Alexander J, Thomsen C, Chatzi L, Gützkow KB, Grazuleviciene R, Martens DS, Plusquin M, Slama R, McEachan RC, Wright J, Yang TC, Urquiza J, Tamayo I, Sunyer J, Vafeiadi M, Nawrot TS, Vrijheid M

Telomere length and mitochondrial DNA content are considered biomarkers of cellular aging, oxidative stress, and inflammation, but there is almost no ... Read More

Source: PubMed
JACC Basic Transl Sci      

Telomeres as Therapeutic Targets in Heart Disease.

Yeh JK, Lin MH, Wang CY

Telomeres are double-stranded repeats of G-rich tandem DNA sequences that gradually shorten with each cell division. Aging, inflammation, and oxidativ ... Read More

Source: PubMed
Rejuvenation Res   2020 Jan 28   

IS THE LEUKOCYTE TELOMERE LENGTH ASSOCIATED WITH DECREASED PHYSICAL FUNCTIONAL CAPACITY IN THE ELDERLY?

Pereira FSM, Thomasini RL, Lustosa LP, Pereira DSS, Pereira LSM, Kassab GBI, Silva TJ, Guerra RO, Parentoni AN

Leukocyte telomere length in the elderly has been positively associated with healthy living and physical activity. Factors that interfere with telomer ... Read More

Source: PubMed
Aging Cell   2020 Jan 28   

Mitochondrial function in skeletal myofibers is controlled by a TRF2-SIRT3 axis over lifetime.

Robin JD, Jacome Burbano MS, Peng H, Croce O, Thomas JL, Laberthonniere C, Renault V, Lototska L, Pousse M, Tessier F, Bauwens S, Leong W, Sacconi S, Schaeffer L, Magdinier F, Ye J, Gilson E

Telomere shortening follows a developmentally regulated process that leads to replicative senescence of dividing cells. However, whether telomere chan ... Read More

Source: PubMed
BMJ Open      

A multidisciplinary approach to mental illness: do inflammation, telomere length and microbiota form a loop? A protocol for a cross-sectional study on the complex relationship between inflammation, telomere length, gut microbiota and psychiatric disorders.

Manchia M, Paribello P, Arzedi C, Bocchetta A, Caria P, Cocco C, Congiu D, Cossu E, Dettori T, Frau DV, Garzilli M, Manca E, Meloni A, Montis MA, Mura A, Nieddu M, Noli B, Pinna F, Pisanu C, Robledo R, Severino G, Sogos V, Chillotti C, Carpiniello B, Del Zompo M, Ferri GL, Vanni R, Squassina A

Severe psychiatric disorders are typically associated with a significant reduction in life expectancy compared with the general population. Among the ... Read More

Source: PubMed

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