Hum Exp Toxicol 2020 Jan 30
Thiamine deficiency and oxidative stress induced by prolonged metronidazole therapy can explain its side effects of neurotoxicity and infertility in experimental animals: Effect of grapefruit co-therapy.
Hassan MH, Awadalla EA, Ali RA, Fouad SS, Abdel-Kahaar E
We aimed to explore the possible neurotoxicity and infertility mechanisms of prolonged metronidazole (MTZ) use and the effects of antioxidant grapefru ...
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Source: PubMed
Pathol. Int. 2020 Jan 29
Frequent EGFR expression/EGFR amplification and lack of activating mutation in testicular choriocarcinoma.
Miyai K, Ito K, Matsukuma S, Tsuda H
Choriocarcinoma (CC) is the rarest but most aggressive histological component of adult testicular germ cell tumor (TGCT). Although we previously repor ...
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Source: PubMed
J Family Reprod Health
A Rare Case of Serous Papillary Ovarian Epithelial Type Carcinoma in Testis: A Rare Testicular Neoplasm.
Abdollahi A, Ensani F, Ayati M, Jahanian S, Eftekhar Javadi A, Khorsand A
Ovarian epithelial type carcinomas of testis are an extremely rare group of tumors, a few cases of which having been reported. We present the case of ...
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Source: PubMed
Ann. Oncol.
Sperm count in Swedish clinical stage I testicular cancer patients following adjuvant treatment.
Weibring K, Nord C, Ståhl O, Eberhard J, Sandberg K, Johansson H, Arver S, Giwercman A, Cohn-Cedermark G
Little is known regarding sperm production following adjuvant treatment in testicular cancer (TC) clinical stage I (CS I) patients. ...
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Source: PubMed
J. Leukoc. Biol. 2020 Jan 27
RIP1 kinase activity is critical for skin inflammation but not for viral propagation.
Webster JD, Kwon YC, Park S, Zhang H, Corr N, Ljumanovic N, Adedeji AO, Varfolomeev E, Goncharov T, Preston J, Santagostino SF, Patel S, Xu M, Maher J, McKenzie BS, Vucic D
Receptor interacting protein kinase 1 (RIP1) is a critical effector of inflammatory responses and cell death activation. Cell death pathways regulated ...
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Source: PubMed
