Med. J. Malaysia
Prevalence of endocrine complications in transfusion dependent thalassemia in Hospital Pulau Pinang: A pilot study.
Lee KT, Lim SL, Goh AS
Frequent blood transfusions results in iron overload and lead to multiple endocrine complications. In spite of improvements in iron chelation therapy, ...
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Source: PubMed
Nutrition
Zinc supplementation improves glucose homeostasis in patients with ß-thalassemia major complicated with diabetes mellitus: A randomized controlled trial.
Matter RM, Elbarbary NS, Ismail EAR, Darwish YW, Nada AS, Banoub VP
The development of abnormal glucose tolerance in ß-thalassemia major (ß-TM) is associated with alterations in the oxidant-antioxidant status. Zinc is ...
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Source: PubMed
Biol. Blood Marrow Transplant. 2020 Jan 30
Goal-oriented monitoring of cyclosporine is effective for graft-versus-host disease prevention after Hematopoietic Stem Cell Transplantation in Sickle Cell Disease and Thalassemia major.
Gauthier A, Bleyzac N, Garnier N, Kebaili K, Joly P, Goutagny MP, Mollet I, Goutelle S, Renard C, Bertrand Y
Graft-versus-host disease (GvHD) is an important challenge and one of the major causes of morbidity and mortality in children after hematopoietic stem ...
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Source: PubMed
J. Med. Genet. 2020 Jan 31
ATR-16 syndrome: mechanisms linking monosomy to phenotype.
Babbs C, Brown J, Horsley SW, Slater J, Maifoshie E, Kumar S, Ooijevaar P, Kriek M, Dixon-McIver A, Harteveld CL, Traeger-Synodinos J, Wilkie AOM, Higgs DR, Buckle VJ
Deletions removing 100s-1000s kb of DNA, and variable numbers of poorly characterised genes, are often found in patients with a wide range of developm ...
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Source: PubMed
BMC Cancer
Incidence of biomarkers in high-grade gliomas and their impact on survival in a diverse SouthEast Asian cohort - a population-based study.
Ang SYL, Lee L, See AAQ, Ang TY, Ang BT, King NKK
Gliomas consist of a heterogeneous group of tumors. This study aimed to report the incidences of O6-methylguanine-DNA-methyltransferase (MGMT) promote ...
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Source: PubMed
