Cancer Sci. 2020 Jan 30
Induction of tryptophan hydroxylase in the liver of subcutaneous tumor model of prostate cancer.
Hagiwara A, Nakamura Y, Nishimoto R, Ueno S, Miyagi Y
Enhanced degradation of tryptophan (Trp) and thus decreased plasma Trp levels are common in several types of cancers. Although it is well known that T ...
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Source: PubMed
BMC Med Imaging
Patient-adapted organ absorbed dose and effective dose estimates in pediatric 18F-FDG positron emission tomography/computed tomography studies.
Quinn BM, Gao Y, Mahmood U, Pandit-Taskar N, Behr G, Zanzonico P, Dauer LT
Organ absorbed doses and effective doses can be used to compare radiation exposure among medical imaging procedures, compare alternative imaging optio ...
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Source: PubMed
J. Inorg. Biochem.
Unprecedented formation of palladium(II)-pyrazole based thiourea from chromone thiosemicarbazone and [PdCl2(PPh3)2]: Interaction with biomolecules and apoptosis through mitochondrial signaling pathway.
Haribabu J, Balachandran C, Tamizh MM, Arun Y, Bhuvanesh NSP, Aoki S, Karvembu R
Two novel pyrazole based thiourea palladium(II) complexes, [PdCl(PPh3)(C9H8NO2S-pz)] (1) and [PdCl(PPh3)(C14H10NO2S-pz)] (2) [pz = pyrazole (C3H2N2)] ...
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Source: PubMed
Aging Cell 2020 Jan 25
Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice.
Yousefzadeh MJ, Zhao J, Bukata C, Wade EA, McGowan SJ, Angelini LA, Bank MP, Gurkar AU, McGuckian CA, Calubag MF, Kato JI, Burd CE, Robbins PD, Niedernhofer LJ
Senescent cells accumulate with age in vertebrates and promote aging largely through their senescence-associated secretory phenotype (SASP). Many type ...
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Source: PubMed
Nature
Systemic HIV and SIV latency reversal via non-canonical NF-?B signalling in vivo.
Nixon CC, Mavigner M, Sampey GC, Brooks AD, Spagnuolo RA, Irlbeck DM, Mattingly C, Ho PT, Schoof N, Cammon CG, Tharp GK, Kanke M, Wang Z, Cleary RA, Upadhyay AA, De C, Wills SR, Falcinelli SD, Galardi C, Walum H, Schramm NJ, Deutsch J, Lifson JD, Fennessey CM, Keele BF, Jean S, Maguire S, Liao B, Browne EP, Ferris RG, Brehm JH, Favre D, Vanderford TH, Bosinger SE, Jones CD, Routy JP, Archin NM, Margolis DM, Wahl A, Dunham RM, Silvestri G, Chahroudi A, Garcia JV
Long-lasting, latently infected resting CD4+ T cells are the greatest obstacle to obtaining a cure for HIV infection, as these cells can persist despi ...
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Source: PubMed