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Hormone Replacement Therapy - Side effects and Risks

Risks and Side Effects of HRT

Prolonged use of HRT for more than 10 years can enhance risk of breast and uterine cancer. HRT should be prescribed at the lowest dose possible, for a short duration. Ideally, a re-evaluation with the specialist should be scheduled every six months.

Undoubtedly the treatment has its benefits, but prolonged use of HRT for more than 10 years can enhance risk of breast and uterine cancer. The risk of stroke is also high in the event of prolonged use of HRT.

The risks are non-existent if the treatment is for a short period. Some types of HRT carry an elevated risk and can react differently depending on the health and medical history of the patient.

In the presence of certain medical conditions like excessive vaginal bleeding, medical history of blood clots, breast or uterine cancer, and liver disease, HRT can be commenced only after a thorough analysis by a medical specialist. It is important for the medical specialist and the patient to discuss the side effects and long term risks involved with HRT use. This should help arrive at the best type and dosage of HRT.

HRT should be prescribed at the lowest dose possible, for a short duration. Ideally, a re-evaluation with the specialist should be scheduled every six months.

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When women start taking HRT, they could experience short term side effects, the frequency of which can vary with women. Some of the side effects are:

  • Skin irritation
  • Weight gain
  • Bleeding
  • Mood swings
  • Breast tenderness

Most of these can be improved by making changes in medications or their dosage.


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