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Immune Checkpoint Inhibitors for Cancer Treatment

Immune Checkpoint Inhibitors for Cancer Treatment - Glossary

Glossary

Adverse effect: An unwanted side effects of treatment

Monoclonal antibodies: Laboratory-produced substances that can locate and bind to cancer cells wherever they are in the body. Many monoclonal antibodies are used in cancer detection or therapy; each one recognizes a different protein on certain cancer cells. Monoclonal antibodies can be used alone, or they can be used to deliver drugs, toxins, or radioactive material directly to a tumor.

Cancer: A term for diseases in which abnormal cells divide without control. Cancer cells can invade nearby tissues and can spread through the bloodstream and lymphatic system to other parts of the body.

Immunotherapy: The artificial stimulation of the body's immune system to treat or fight disease.

Tumour mutational burden: The total number of mutations (changes) found in the DNA of cancer cells.

Microsatellite: A short, repeated sequence of DNA

Microsatellite instability: A change that occurs in cancer cells in which the number of repeated DNA bases in a microsatellite is different from what it was when the microsatellite was inherited.

Pharmacovigilance: Science and activities relating to the detection, assessment, understanding, and prevention of adverse effects or any other medicine/vaccine-related problem.


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