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Genetic System

Last Updated on Nov 27, 2023
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Gene

  • A gene is the basic physical and functional unit of heredity. Genes are small sections of DNA that carry genetic information (1 Trusted Source
    Basic Genetics Information

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    ).
  • The human genome contains approximately between 20,000 and 25,000 genes (2 Trusted Source
    What is a gene?

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    ).
  • Every person has two copies of each gene, one inherited from the mother and one from the father (3 Trusted Source
    Why is genetics important to my family and me?

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    ).
  • All humans are 99.9% genetically identical; only 0.1% of our genetic make-up differs (4 Trusted Source
    Genetics vs. Genomics Fact Sheet

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    ).
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Chromosome

  • Chromosomes exist in pairs. Human cells normally have 23 pairs of chromosomes (total 46 chromosomes).
  • Chromosomes are divided into 22 numbered pairs (autosomes) and one sex chromosome pair (5 Trusted Source
    Chromosomal DNA and Its Packaging in the Chromatin Fiber

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    ).

Sex Chromosomes

  • Sex chromosomes (X and Y) are specialized chromosomes that carry genes that determine an individual's sex (6 Trusted Source
    Sex Chromosome

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    ).
  • Females have two X chromosomes, and males have one X and one Y chromosome (7 Trusted Source
    Chromosome

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    ).
  • The child inherits an X chromosome from his mother. The father may provide an X or a Y. The father's chromosome determines whether the child is born male or female.
  • The X chromosome is around three times larger than the Y chromosome, with approximately 900 genes, whereas the Y chromosome contains only 55 genes (8 Trusted Source
    Y Chromosome Infographic

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    ).
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Chromosome 9

  • The gene that determines the blood group of an individual is found on chromosome 9 (9 Trusted Source
    A Brief History of Human Blood Groups

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    ).

Siblings

  • Siblings share an average of 50% of their genes (10 Trusted Source
    Why are siblings so different? The significance of differences in sibling experiences within the family

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    ).

Identical Twins

  • Identical twins have identical DNA but not identical fingerprints (11 Trusted Source
    Are fingerprints determined by genetics?

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    ).
  • On average, dizygotic or non-identical twins share 50% of their genes, whereas identical or monozygotic twins share 100% of their genes (12 Trusted Source
    Twin Studies: A Unique Epidemiological Tool

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    ).

Genetic Disorders

  • Genetic conditions are caused by mutations in one or more genes that are passed down from parents to offspring (13 Trusted Source
    Genetic Disorders

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    ).
  • Consanguineous marriage (cousin marriage) increases the risk of genetic diseases in offspring (14 Trusted Source
    Genes and genetics

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    ).

References:

  1. Basic Genetics Information - (https://www.ncbi.nlm.nih.gov/books/NBK115558)
  2. What is a gene? - (https://medlineplus.gov/genetics/understanding/basics/gene)
  3. Why is genetics important to my family and me? - (https://www.ncbi.nlm.nih.gov/books/NBK115604/)
  4. Genetics vs. Genomics Fact Sheet - (https://www.genome.gov/about-genomics/fact-sheets/Genetics-vs-Genomics)
  5. Chromosomal DNA and Its Packaging in the Chromatin Fiber - (https://www.ncbi.nlm.nih.gov/books/NBK26834/)
  6. Sex Chromosome - (https://www.genome.gov/genetics-glossary/Sex-Chromosome)
  7. Chromosome - (https://medlineplus.gov/ency/article/002327.htm)
  8. Y Chromosome Infographic - (https://www.genome.gov/about-genomics/fact-sheets/Y-Chromosome-facts)
  9. A Brief History of Human Blood Groups - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595629/)
  10. Why are siblings so different? The significance of differences in sibling experiences within the family - (https://pubmed.ncbi.nlm.nih.gov/1955016/)
  11. Are fingerprints determined by genetics? - (https://medlineplus.gov/genetics/understanding/traits/fingerprints/)
  12. Twin Studies: A Unique Epidemiological Tool - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919929)
  13. Genetic Disorders - (https://www.genome.gov/For-Patients-and-Families/Genetic-Disorders)
  14. Genes and genetics - (https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/genes-and-genetics)
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