Conn's Syndrome

• Bilateral or unilateral adrenal Hyperplasia
• Adrenal adenoma
• Familial hyperaldosteronism - Types I and II
• Unilateral adrenocortical carcinoma

• High blood pressure
• Low levels of potassium
• Low blood pH levels
• Fatigue
• Cramping
• Chronic headaches
• Palpitations
• Myalgia, muscle weakness or numbness
• Polydipsia (excessive thirst) and polyuria (increased urination) may be present
• Patients with long-standing hypertension may show the presence of cardiac and neurological problems.

Clinical Examination
• PAC to PRA ratio: Ratio of Plasma aldosterone
• Concentration to plasma renin activity
• Captopril suppression test
• 24-hour urinary excretion of aldosterone test
• Saline suppression test
• CT Scan

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