Just one-fifth of the standard dose of a commonly used meningitis vaccine can turn out to be as effective as using the full dose, according to a new study.
A new study has discovered that just one-fifth of the standard dose of the commonly used meningitis vaccine is as effective as the full dose.
Scientists hope that this new finding may allow scarce vaccine resources to be stretched further, especially during epidemics in Africa.
Meningitis - Causes - Symptoms - Diagnosis - Treatment - FAQs
Meninges are the three layers of membrane that cover the brain and infection of the cerebrospinal fluid between them causes meningitis the disease of the meninges.
Meninges are the three layers of membrane that cover the brain and infection of the cerebrospinal fluid between them causes meningitis the disease of the meninges.
Scientists conducted a randomized clinical trial of 750 healthy volunteers (2-19 years old) in Uganda in 2004.
Their immune response, assessed by serum bactericidal activity (SBA), was measured for 1/5 and 1/10 doses compared to a full dose. SBA response and safety/tolerability using 1/5 dose were comparable to a full dose for three serogroups (A, Y, W135), but not a fourth (C).
Hib Vaccine - Types, Dosage Schedule, Contraindications and Side Effects
The Hib vaccine protects children against infections like meningitis and pneumonia that are caused by the Haemophilus influenzae type b bacterium.
The Hib vaccine protects children against infections like meningitis and pneumonia that are caused by the Haemophilus influenzae type b bacterium.
The study's findings were used for a 2007 WHO recommendation that a fractional dosing strategy be utilized in the event of severe vaccine shortages during a meningitis epidemic.
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Enzyme Behind Meningitis Identified
Australian researchers have identified the enzyme that could be behind infections such as meningitis and bactremia. This could pave the way for more targeted therapy.
Australian researchers have identified the enzyme that could be behind infections such as meningitis and bactremia. This could pave the way for more targeted therapy.
Source-ANI
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Meningitis - Medical Profession Has Not Learnt Its Lessons, Complains Father of Welsh Victim
The medical profession has not learned from its mistakes and misdiagnoses in regard to meningitis, complains a Welsh man whose son died of the disease 16 years ago.
The medical profession has not learned from its mistakes and misdiagnoses in regard to meningitis, complains a Welsh man whose son died of the disease 16 years ago.
