The last structure of Aromatase, an enzyme used by the human body to create estrogen, has been determined by a researcher from HWI, to help in breast cancer cure.
A researcher at Hauptman-Woodward Medical Research Institute has moved a step closer to a cure, and possibly the prevention, of the most common type of breast cancer.
Debashis Ghosh, a senior research scientist, reached a milestone by determining the third and last structure of Aromatase, an enzyme used by the human body to create estrogen.
Breast Cancer - Causes, Risks, Symptoms, Diagnosis, Staging, Treatment, Prevention & Prognosis
Breast cancer is a cancer that affects the breasts or mammary glands. Early detection and lifestyle changes help in controlling breast cancer.
Breast cancer is a cancer that affects the breasts or mammary glands. Early detection and lifestyle changes help in controlling breast cancer.
"This is a dream come true," Dr. Debashis Ghosh, an HWI senior research scientist and a principal investigator who also holds a joint faculty appointment at the Roswell Park Cancer Institute (RPCI), said.
"Scientists worldwide have been trying for 35 years to crystallize this membrane-bound enzyme and we are the first to succeed. Now that we know the structures of all three key enzymes implicated in estrogen-dependant breast cancers, our goal is to have a personalized cocktail of inhibitors customized to the specific treatment needs of each patient.
Interesting Facts About Breast Cancer
Breast cancer is the most commonly diagnosed cancer in women and in 2020 and nearly 2.3 million breast cancers were diagnosed globally.
Breast cancer is the most commonly diagnosed cancer in women and in 2020 and nearly 2.3 million breast cancers were diagnosed globally.
Walter Pangborn, executive vice president at HWI, said: "This means that results from this research will form the basis for novel breast cancer drugs that are highly specific for aromatase, but cause minimal side effects."
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Breast Self Examination
Slides and animation of Breast Self Examination for early detection of breast cancer lumps in women
Slides and animation of Breast Self Examination for early detection of breast cancer lumps in women
Source-ANI
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Elevated Estrogen Levels Increase The Risk Of Breast Cancer Recurrence
Researchers at the University of California, San Diego, have found out that the blood taken from the women whose breast cancer recurred, showed twice the level of estrogen when compared to the
Researchers at the University of California, San Diego, have found out that the blood taken from the women whose breast cancer recurred, showed twice the level of estrogen when compared to the
