Intranasal ketamine has minor side effects than intranasal fentanyl in children with acute pain who had fractures in their extremities.
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‘There is no difference in the efficacy or pain relief between intranasal ketamine and intranasal fentanyl.’
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Reynolds and colleagues, in their exploratory analysis, detected no difference in efficacy or pain relief between the two drugs. Additionally, no patient in either group experienced a serious adverse event, and none of the side effects required intervention. ![twitter](https://images.medindia.net/icons/news/social/twitter.png)
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Based on their findings, Reynolds, et al, recommends a larger, multicenter, non-inferiority study to more rigorously evaluate the safety, efficacy, and potential opioid-sparing benefits of intranasal ketamine analgesia for children with acute pain.
"There is less information about ketamine available than is needed to determine its role as first line pain therapy in children. This study starts to give us the information necessary to determine ketamine's place as a pain medication and its potential to replace opioids," said James R. Miner, MD, FACEP, chief of emergency medicine at the Hennepin County Medical Center and professor of emergency medicine at the University of Minnesota.
Source-Eurekalert