Alzheimer's Risk High in Depressed People With Memory Problems

A new study has revealed that depressed individuals with memory problems are more likely to develop Alzheimer's disease

A new study has revealed that depressed individuals with memory problems are more likely to develop Alzheimer's disease compared to people who are not depressed.

The research has been published in the June 16, 2009, print issue of Neurology, the medical journal of the American Academy of Neurology. However, the research also shows that the popular Alzheimer's drug donepezil may delay the progression to Alzheimer's disease for depressed people with mild cognitive impairment (MCI) or memory problems.

Depression - Types, Causes, Symptoms, Diagnosis, Treatment
Depression is one of the most common mental disorders affecting approximately 340 million people in the world. No one is immune from depression - it occurs in people of all social classes, all countries and all cultural settings.

MCI is described as the period in-between normal aging and Alzheimer's disease. A person with MCI experiences memory problems that are greater than expected with normal aging but does not show other symptoms of Alzheimer's disease, such as difficulties in completing everyday activities.

To reach the conclusion, researchers followed 756 people with MCI who were between the ages of 55 and 91 for three years. Of those, 208 were diagnosed with depression using a test that measures the severity and intensity of a person's depressive symptoms. For every one point increase on the test, a participant's risk of developing Alzheimer's disease went up by three percent.

"Our longer term findings add to the body of evidence that suggests depression is a major risk factor for Alzheimer's disease," said study author Po H. Lu, PsyD, assistant professor of neurology with the David Geffen School of Medicine at UCLA in Los Angeles.

Adolescent Depression - Causes - Affects - Depressed Teens - Treatment - FAQs
Adolescent depression is an ailment that occurs during the teenage characterized by persistent melancholy, disappointment and loss of self-esteem.

"Since the drug donepezil has been shown to improve the behavioral symptoms of Alzheimer's disease, our study also tested whether the drug would delay the progression to Alzheimer's disease in people with memory problems," the expert added.

Participants were given either vitamin E, donepezil or a placebo pill. The study found that at 1.7 years, among depressed people with mild cognitive impairment, 11 percent of those taking donepezil developed Alzheimer's disease compared to 25 percent of those who took vitamin E or placebo. At 2.2 years, 14 percent of those taking donepezil developed Alzheimer's compared to 29 percent of those who took vitamin E or placebo. Donepezil had little effect in the group of people who were not depressed.

Andropause - Male menopause - Symptoms - Causes - Diagnosis - Treatment
Andropause or male menopause causing low libido in a man is due to decreasing level of male hormones, like testosterone. Symptoms of andropause are depression, irritability.

"If we can delay the progression of this disease for even two years, it could significantly improve the quality of life for many people dealing with memory loss," said Lu.

Source-ANI
RAS

Overview Suicide
Suicide is an act of ending one's own life and it usually results from emotional isolations and inability to adjust and cope with one's environment.