Better Control of Foodborne Disease With Whole Genome Sequencing

Whole genome sequencing (WGS) helps improve detection of and response to food borne illnesses and outbreaks.

Bacterial diarrhoea, resulting in 230 000 deaths each year is due to eating contaminated food and almost 1 in 10 people worldwide fall ill every year.

In an article in Eurosurveillance PulseNet International advocates for public health institutes and laboratories around the world to move together towards the use of whole genome sequencing (WGS) to improve detection of and response to foodborne illnesses and outbreaks.

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‘Whole genome sequencing (WGS) will save lives and money due to the superior ability of WGS to link human cases with contaminated food sources.’

PulseNet International is a global network of public health laboratory networks, dedicated to bacterial foodborne disease surveillance. The network is comprised of the national and regional laboratory networks of USA, Canada, Latin America and the Caribbean, Europe, Africa, the Middle-East and Asia Pacific.

The European Centre for Disease Prevention and Control (ECDC) manages the EU/EEA food- and waterborne diseases and zoonoses network of public health institutes and laboratories, which work to ensure comparability of data and further ties to the global health community.

Mike Catchpole, Chief Scientist at ECDC says, "it is important for all partners worldwide to continue to work together towards the implementation and standardised analysis of whole genome sequencing."

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The article also states that a global standard method for primary sequence data analysis based on whole genome Multiple Locus Sequence Typing (wgMLST) and derived public nomenclature will be adopted.

This will facilitate the sharing of information within regional and global public health laboratory networks, increasing efficiency and enabling data to be compared across countries in real-time which is currently not the case. This is especially important due to international travel and trade.

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Common steps for validation studies, development of standardised protocols, quality assurance programmes and nomenclature have been agreed.

Source-Eurekalert

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