Broccoli Sprouts Help In Treating Type 2 Diabetes

Globally, more than 300 million people are affected with Type 2 diabetes, and when given concentrated broccoli sprout, fasting blood glucose levels decreased.

Type 2 diabetes patients can now manage their blood sugar levels with concentrated broccoli sprout extract, reveals a new study.

The findings could offer a much needed alternative to address the condition, which has become a worldwide epidemic.

Broccoli-related Compound Yields Possible Treatment for Eye Disease
I3C compound in broccoli helps activate the aryl hydrocarbon receptor protein which involves in chemical detoxification but declines with aging.

‘Sulforaphane, a chemical compound that occurs naturally is found in cruciferous vegetables, and is used to lower blood glucose levels in Type 2 Diabetic patients.’

Type 2 diabetes afflicts more than 300 million people globally, and as many as 15% of those patients cannot take the first-line therapy metformin because of kidney damage risks.

Seeking a more viable path forward, Annika Axelsson and colleagues used a computational approach to identify compounds that might counter the disease-associated gene expression changes associated with type 2 diabetes.

The researchers constructed a signature for type 2 diabetes based on 50 genes, then used publically available expression datasets to screen 3,852 compounds for drugs that potentially reverse disease.

Broccoli-Gate Revived By Obama
Clearly hitting close to home is Michelle Obama's healthy eating campaign.

The most promising chemical sulforaphane, a naturally occurring compound found in cruciferous vegetables tamped down glucose production by liver cells growing in culture, and shifted liver gene expression away from a diseased state in diabetic rats.

When the researchers gave concentrated broccoli sprout extracts to 97 human type 2 diabetes patients in a 12-week randomized placebo-controlled trial, obese participants who entered the study with dysregulated disease demonstrated significantly decreased fasting blood glucose levels compared to controls.

Fight Obesity, Cancer: Add Broccoli Sprouts To Your Diet
A natural compound in broccoli sprouts help detoxify cancer producing compounds and activates fat burning in cells.

The authors say developing gene signatures to investigate large public repositories of gene expression data could be a valuable strategy to rapidly identify clinically relevant compounds.

Broccoli's Cancer-fighting Potential, Enhanced
By simply spraying a plant hormone on broccoli, one of the most nutritious foods in the world, its cancer-fighting potential can be boosted, researchers claim

Source-Eurekalert