The new genetic test based on AI and ML has proven effective to identify patients who do not require PARP inhibitors commonly used to treat ovarian cancer.
Genetic Testing for Ovarian Cancer
"The genetic test helps to identify patients who do not benefit from the drug, thus avoiding unnecessary treatment and the adverse effects associated with the drug," Anniina Farkkila from Helsinki University Hospital was quoted as saying in the statement.
Ovarian Cancer | Cancer in the Ovaries - Causes, Symptoms, Treatment & Prevention
Ovarian cancer affects both the ovaries and is referred to as the 'silent killer' as the symptoms go unnoticed until the disease advances.
Ovarian cancer affects both the ovaries and is referred to as the 'silent killer' as the symptoms go unnoticed until the disease advances.
‘PARP inhibitors have achieved excellent results as a maintenance treatment after surgery and cytostatic therapy of newly diagnosed ovarian cancer patients.’
"Roughly half of ovarian cancers have a deficiency in a specific DNA (deoxyribonucleic acid) repair pathway. Cancer cells with this deficiency are unable to accurately repair breaks in the DNA double-strand, which causes the accumulation of DNA lesions," doctoral researcher Fernando Perez-Villatoro from the University of Helsinki said. The study results show that each cancer type is associated with different characteristics of the genetic lesions related to homologous recombination DNA-repair deficiency (HRD), which is a common driver of genomic instability. Therefore, developing a test optimized for ovarian cancer was important for advancing the precision of therapies for the cancer type, the University of Helsinki noted.
The study results were published in the latest issue of npj Precision Oncology.
About Cancer in Women
Cancer is one of the frequently talked about and most feared disease that falls under the genre of lifestyle diseases that have evolved, rather rapidly, in the past two decades.
Cancer is one of the frequently talked about and most feared disease that falls under the genre of lifestyle diseases that have evolved, rather rapidly, in the past two decades.
Quiz on Ovarian Cancer / Cancer of the Ovary
Ovarian cancer is a cancer that does not produce definite symptoms. Here are a few questions that you could attempt to answer to check your knowledge on ovarian cancer.
Ovarian cancer is a cancer that does not produce definite symptoms. Here are a few questions that you could attempt to answer to check your knowledge on ovarian cancer.
Female Reproductive System
Interactive section of Medindia gives details regarding Female reproductive system showing how the sperm fetilize the eggs
Interactive section of Medindia gives details regarding Female reproductive system showing how the sperm fetilize the eggs
