Can Physical Exercises Delay Memory Problems in Alzheimer's Patients?

Aerobic exercise training may delay the decline in memory function that occurs in individuals who are at risk of developing or have been diagnosed with Alzheimer's disease.

Physical exercise may help delay cognitive (memory) function loss in patients with Alzheimer's disease finds a new study. The findings of this study are published in the Journal of the American Geriatrics Society.

Alzheimer's disease is a brain disorder that destroys memory and thinking skills over time. It is the most common form of dementia in older adults.

Biochip Test may Help Doctors to Predict the Risk of Alzheimer Disease
The biochip test is as accurate as existing molecular tests that analyze the DNA for identifying the patients who are at an elevated risk of Alzheimer's disease.

‘Older adults who are at risk of developing Alzheimer's disease or those who already have the disease may be able to preserve their ability to think and make decisions by doing aerobic exercises.’

There is presently no cure for the condition, though treatment options are available. Geriatrics experts have suggested that exercising can improve brain health in older adults.

Today, some 5.3 million Americans live with Alzheimer's disease, and it is now the sixth leading cause of death in the United States. The number of older adults who will develop AD is expected to more than triple by 2050.

The World Health Organization (WHO) has recommendations suggests that older adults Should perform 150 minutes a week of moderate exercises (such as brisk walking), 75 minutes a week of vigorous aerobic training, or a combination of the two types. It also recommends older adults perform muscle-strengthening exercises on at least two or more days a week.

Diagnostic Accuracy of Cerebral Spinal Fluid Biomarkers for Alzheimer Disease
Bottom Line: Cerebral spinal fluid (CSF) levels of β-amyloid 42(Aβ42) are linked with the diagnosis of Alzheimer disease (AD) and (Aβ) accumulation in the brain independent of apolipoprotein E (APOE) gene makeup.

However, not all studies of exercise and older adults have proven the benefits of exercise. We don't know for sure whether exercise slows mental decline or improves older adults' ability to think and make decisions.

A team of researchers designed a study to learn whether exercise could delay or improve Alzheimer's disease symptoms. They reviewed 19 studies that examined the effect of an exercise training program on cognitive function in older adults who were at risk for or diagnosed with Alzheimer's disease.

Survey Examines Recessive Alzheimer Disease Gene
Runs of homozygosity (ROHs, regions of the genome where the copies inherited from parents are identical) may contribute to the etiology (origin) of Alzheimer disease (AD).

The studies included 1,145 older adults, most of whom were in their mid-to-late 70s. Of the participants, 65 percent were at risk for Alzheimer's disease and 35 percent had been diagnosed with Alzheimer's disease. The researchers published their findings in the Journal of the American Geriatrics Society.

As the researchers examined the studies, they discovered that older adults who did aerobic exercise by itself experienced three times greater level of improvement in cognitive function than those who participated in combined aerobic training and strength training exercises.

Study Examines Cognitive Impairment Consistent With Alzheimer Disease in Families With Exceptional Longevity
A study examines the relationship between families with exceptional longevity and cognitive impairment consistent with Alzheimer disease.

The researchers also confirmed that the amount of exercise WHO recommends for older adults was reinforced by the studies they examined.

Finally, the researchers found that older adults in the no-exercise control groups in the studies faced declines in cognitive function. Meanwhile, the older adults who exercised showed small improvements in cognitive function no matter what type of exercise they did.

The research team concluded that this study may be the first to show that for older adults who are at risk for or who have AD, aerobic exercise may be more effective than other types of exercise in preserving the ability to think and make decisions.

The researchers note that their findings need to be confirmed in future studies.

Source-Eurekalert