Scientists have discovered an intra cellular pathway, initially not associated with breast cancer, as a driving force behind the highly fatal sub-type of disease.
Scientists have discovered an intra cellular pathway, initially not associated with breast cancer, as a driving force behind the highly fatal sub-type of disease.
Researchers at UCLA's Jonsson Comprehensive Cancer Center found that that the sub-type of cancer was disproportionately over-represented in African American women.
Breast Cancer - Causes, Risks, Symptoms, Diagnosis, Staging, Treatment, Prevention & Prognosis
Breast cancer is a cancer that affects the breasts or mammary glands. Early detection and lifestyle changes help in controlling breast cancer.
Breast cancer is a cancer that affects the breasts or mammary glands. Early detection and lifestyle changes help in controlling breast cancer.
According to Tim Lane, researcher and senior author of the paper, the pathway regulates how cells identify and destroy proteins and represents a class of genes called proteasome targeting complexes.
The study observed that basal cancer cells made a new type of proteasome targeting complex while degrading the tumor suppressor gene p27 - one of a handful of proteins that are expressed in normal cells and act to prevent rapid cell growth, indicative of cancer.
Breast Self Examination
Slides and animation of Breast Self Examination for early detection of breast cancer lumps in women
Slides and animation of Breast Self Examination for early detection of breast cancer lumps in women
He said: "The possibility that this new proteasome targeting complex might provide targets for therapeutic intervention is a completely new area for breast cancer research.
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Breast Biopsy - Fine Needle Aspiration Cytology - Core Needle Biopsy - Vacuum-Assisted Biopsy - Excision Biopsy - FAQs
Breast biopsy involves removing a sample of breast tissue to determine whether it is cancerous or benign.
Breast biopsy involves removing a sample of breast tissue to determine whether it is cancerous or benign.
The research, done in animal models and human breast cancer cell lines, has been published in the November 15 issue of the journal Genes and Development.
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About Cancer in Women
Cancer is one of the frequently talked about and most feared disease that falls under the genre of lifestyle diseases that have evolved, rather rapidly, in the past two decades.
Cancer is one of the frequently talked about and most feared disease that falls under the genre of lifestyle diseases that have evolved, rather rapidly, in the past two decades.
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