Cesarean section delivery and prolonged labor can cause changes in infant's gut microbes and may lead to increased risk of allergies and childhood obesity, reports a new study.

‘Infants born after prolonged labor or C-section delivery are found to be at higher risk of allergies and childhood obesity.’

They linked factors like prolonged labor and cesarean section delivery to changes in the infant's gut microbes. They then discovered the pathways by which these changes may lead to an enhanced risk of allergies and obesity later in childhood.




Senior author Anita Kozyrskyj said the findings highlight the importance of recognizing multiple and common pathways of the gut microbiome during infancy.
"Much of what occurs to us later in life is linked to the exposures we face in infancy and early childhood," she stated. "Understanding how disturbances to the gut microbiome influence health in later childhood means we may have various options for effective interventions to prevent these chronic conditions before they become established."
The study revealed that infants born by cesarean section were more likely to have a high body mass index (BMI)score at ages 1 and 3. When the researchers analyzed the children's microbiome profiles at 3 months of age, they found that an altered ratio of two types of bacteria, Enterobacteriaceae and Bacteroidaceae, was the dominant path to overweight.
The takeaway from this study is that exposures at birth could trigger multiple and common gut microbial pathways leading to childhood obesity and allergic sensitization.
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Source-Medindia