Citalopram Boosts the Differentiation Efficacy of BMSCs into Neuronal-like Cells

Selective serotonin reuptake inhibitor antidepressants can actually promote the proliferation of neuronal cells and boost neuroplasticity in both in vitro and in vivo, evidence suggests

Selective serotonin reuptake inhibitor antidepressants can actually promote the proliferation of neuronal cells and boost neuroplasticity in both in vitro and in vivo, evidence suggests. Dr. Javad Verdi and his team, Tehran University of Medical Sciences, Iran proposed that citalopram, a selective serotonin reuptake inhibitor, can increase the efficacy of bone marrow mesenchymal stem cells (BMSCs) differentiating into neuronal-like cells.

Experimental results confirmed that citalopram can improve the neuronal-like cell differentiation of BMSCs by increasing cell proliferation and survival while maintaining their neuronal characteristics. These results were published in Neural Regeneration Research (Vol. 9, No. 8, 2014).

Drugs Causing Weight Gain
Medications are among the lesser-known yet common causes of weight gain. Switching over to a lesser weight-promoting alternative can help to solve the issue of weight gain with medications.

Source-Eurekalert

Cognitive Behavioral Therapy in Pediatric Antidepressant Treatment Reduces Likelihood of Relapse
A new UT Southwestern Medical Center study indicates that cognitive behavioral therapy in addition to medication improves the long-term success of treatment for children and adolescents suffering from depression.