Common Nasal Decongestant Ups Stroke Risk

As per the French medicines agency, decongestant medications containing pseudoephedrine when taken orally may elevate the risk of stroke or heart attack. These products include well-known brands like Sudafed, Galpseud, Boots Decongestat, Care //Decongestant, Actifed Rhume, Doliruhm Paracetamol and Pseudoephedrine, and Humex Rhume, among others. (1^✔ ✔Trusted Source
National Agency for the Safety of Medicines and Health

Go to source) "The message is clear. Do not use them. We do not risk getting a stroke for a stuffy nose," Christelle Ratignier-Carbonneil, the director of France's National Agency for the Safety of Medicines and Health Products (ANSM), (1^✔ ✔Trusted Source
National Agency for the Safety of Medicines and Health

Go to source) was quoted as saying to public broadcaster FranceInfo.

Concerns Surrounding Pseudoephedrine Decongestants

Many are available as oral tablets without a prescription or as a nasal spray with a prescription, the ANSM said. Pseudoephedrine, a widely used decongestant, works by narrowing the blood vessels in your nose. However, it can also narrow blood vessels in other parts of the body, raising blood pressure and heart rate, Euronews reported. (2^✔ ✔Trusted Source
French medicines agency warns not to use nasal decongestant cold medicines over stroke risk

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While the common decongestant is considered safe for most people, the advisories underscore the importance of consulting with healthcare professionals before starting any new medication, particularly for individuals with underlying health conditions or those taking other medications.

The Belgian health authorities said that the benefits of the medications outweigh the minimal risk of serious side effects. They argued that the benefit-risk balance for cold medicines containing pseudoephedrine remains positive, due to the extremely rare occurrence of serious side effects and the effective relief these medicines provide for cold symptoms, BNN Breaking reported.

FDA Declares Phenylephrine as Ineffective Nasal Decongestant Replacement

Meanwhile, the US Food and Drug Administration (FDA) recently deemed another drug called phenylephrine ineffective. It is used to replace pseudoephedrine in some nasal decongestants. The decision was made unanimously by 16 members of the FDA's Nonprescription Drugs Advisory Committee (NDAC) that oral phenylephrine, a component found in common medications like Sudafed, Mucinex, Vicks, Allegra, and Dayquil, does not effectively provide relief from nasal congestion.

The FDA further clarified that these cold medicines do not violate any safety concerns associated with the use of oral phenylephrine at the recommended dose.

References:

1. National Agency for the Safety of Medicines and Health - (https://gnius.esante.gouv.fr/en/players/player-profiles/national-agency-safety-medicines-and-health-products-ansm)
2. French medicines agency warns not to use nasal decongestant cold medicines over stroke risk - (https://www.euronews.com/next/2023/10/23/french-medicines-agency-warns-not-to-use-nasal-decongestant-cold-medicines-over-stroke-ris)

Source-IANS