New study highlights the role of astrocytes in the development of epilepsy following the most common type of traumatic brain injury in humans.
In mice model, a cellular response to repeated concussions that may contribute to seizures has been discovered by scientists. The study, published in JNeurosci, establishes a new animal model that could help improve our understanding of //post-traumatic epilepsy.
Stefanie Robel, Oleksii Shandra and colleagues induced mild traumatic brain injury in mice to mimic blows to the head that result in human concussions.
A unique population of astrocytes responded to these injuries and the researchers observed spontaneous recurrent seizures in some mice within one month.
Source-Eurekalert