COVID-19 can Impact Young Children's Hearts, Says Study

A case revealed that a 2-month-old infant diagnosed with coronavirus experienced reversible myocardial injury and heart failure.

A case revealed that a 2-month-old infant diagnosed with coronavirus experienced reversible myocardial injury and heart failure. The heart complications were similar to COVID-19 related heart issues seen in adults.

The findings were published in JACC: Case Reports. The infant recovered with normal heart function and was discharged with no heart failure medications. "Most children with COVID-19 are either asymptomatic or have mild symptoms, but our case shows the potential for reversible myocardial injury in infants with COVID-19. Testing for COVID-19 in children presenting with signs and symptoms of heart failure is very important as we learn more about the impact of this virus."

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‘Most children with COVID-19 are either asymptomatic or have mild symptoms, but the case study shows the potential for reversible myocardial injury in infants with COVID-19.’

Since the earliest reports of COVID-19 in China, there have been indications of myocardial injury in some patients. In early cohorts of adult patients hospitalized with COVID -19, studies showed as many as between 20-28% of patients showing evidence of myocardial injury. Most of the patients with myocardial injury had pre-existing cardiovascular disease.

In this case, a 2-month-old infant presented with choking and bluish discoloration of the skin after feeding. The child had no history of fever, cough, upper respiratory tract infection symptoms, diarrhea, vomiting or decreased feeding prior to the first presentation. The patient was born pre-maturely at 33 weeks and stayed in the NICU for three weeks, including one week of nasal continuous positive airway pressure.

The patient's initial COVID-19 test was negative, but a repeat test was positive. An ECG showed myocardial injury due to the viral infection and heart failure symptoms exacerbated by the viral infection.

Congestive Heart Failure (Congestive Cardiac Failure) Current Management
Congestive heart failure (CHF) is a condition in which the heart fails to work adequately as a pump that can deliver oxygen rich blood to the body.

Tests ruled out all other possible viral causes for the myocardial injury. The patient required fluid resuscitation and inotropic support for hypotension, as well as mechanical ventilation for respiratory failure. The patient also received remdesivir under a compassionate use order.

"The presentation and clinical course of this patient mirrors four case reports of acute myocardial injury reported in adult patients with COVID-19," said Madhu Sharma, MD, lead author of the case report and a pediatric cardiologist at The Children's Hospital at Montefiore."

Coronavirus
Coronaviruses infect animals, humans, and birds. Human coronaviruses, such as SARS, MERS, and 2019-nCoV cause respiratory distress and even death. The S protein is the infectious agent of the virus.

Source-Eurekalert

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