The COVID-19 virus SARS-CoV-2 infected the kidneys and contributed to tissue scarring. Kidney fibrosis, or scarring, is a serious long-term consequence that can occur virtually after any injury to the kidney.
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‘The kidney organoids were infected with SARS-CoV-2, and the researchers investigated the direct effect of the virus on the kidney cells, independent of potential secondary effects caused by immune cells or other systemic effects.’
The fact that the coronavirus can result in severe damage in the human body is known, and also that the kidneys can get infected. But what exactly happens in the kidney due to the infection remains elusive until now. Researchers from the RWTH Uniklinik Aachen, Germany, and the Radboud University Medical Center in The Netherlands, investigated the kidney tissue of COVID-19 patients admitted to the intensive care unit.
The findings, published in the journal Cell Stem Cell, showed scarring of the tissue compared to ICU patients with a non-COVID-19 lung infection and a control group.
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Kidney stones or calculus produces the most severe form of pain in humans. The pain has often been described to be worse than childbirth, broken bones, gunshot wounds, burns, or surgery. Once you form a kidney stone you are always susceptible to another stone. Take this quiz to find out how much do you know about stone disease. Once you complete find out how you fared compared to others who have taken the quiz.
Kidney stones or calculus produces the most severe form of pain in humans. The pain has often been described to be worse than childbirth, broken bones, gunshot wounds, burns, or surgery. Once you form a kidney stone you are always susceptible to another stone. Take this quiz to find out how much do you know about stone disease. Once you complete find out how you fared compared to others who have taken the quiz.
The researchers found, in line with the COVID-19 patient tissues, scarring of the kidney organoids and accompanying signals that contribute to the scarring process.
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"Our work shows kidney scarring in COVID-19 patients, which provides an explanation why the virus might cause kidney functional decline as demonstrated in other studies," added Katharina Reimer from the RWTH.
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Source-IANS
