A strategy for delivering genetic material to the body is tested as a way to repair damaged heart muscle after a heart attack.
What is a Heart Attack | How to Prevent Heart Attacks - Myocardial Infarction Smoking
Heart attack is the death of the heart muscle due to loss of blood supply. Simple guidelines to avoid heart attack are listed.
Heart attack is the death of the heart muscle due to loss of blood supply. Simple guidelines to avoid heart attack are listed.
‘COVID-19 vaccine method shows promise for heart diseases such as heart attack.’
The COVID-19 messenger RNA (mRNA) vaccines use lipid nanoparticles (tiny fat droplets) to deliver mRNA to the body’s cells. This mRNA instructs the cells to manufacture a dummy spike protein on their surface to mimic the protein on the virus causing COVID-19. The body then mounts an immune response by creating antibodies which can be used if the individual becomes infected with the virus.
COVID-19 Vaccine Technique for Heart Disease
A similar method for mRNA delivery was used in the current study. However, instead of aiming for an immune response, the researchers’ ultimate goal is to instruct the heart’s cells to repair themselves after a heart attack.This preliminary study was conducted to determine whether mRNA could be successfully delivered to the heart muscle in lipid nanoparticles. The researchers injected different formulations into the left ventricular wall of mouse hearts during open chest surgery under general anesthesia. Twenty-four hours after administration, the mice were sacrificed and the location of mRNA translation was examined.
The researchers found that mRNA successfully reached the heart cells 24 hours after injection. However, despite injection into the heart, the highest levels of mRNA translation were found in cells of the liver and spleen.
Test Your Knowledge on Coronary Heart Disease
Coronary heart disease is a direct consequence of today’s unhealthy lifestyle and food habits, which include a high-fat diet, inadequate exercise and loads of stress. Coronary heart disease is emerging as an epidemic of the modern world, affecting younger individuals and extending to poorer countries as well. Here is a quiz that will test your knowledge on basic terminology used in coronary heart disease.
Coronary heart disease is a direct consequence of today’s unhealthy lifestyle and food habits, which include a high-fat diet, inadequate exercise and loads of stress. Coronary heart disease is emerging as an epidemic of the modern world, affecting younger individuals and extending to poorer countries as well. Here is a quiz that will test your knowledge on basic terminology used in coronary heart disease.
She concluded: “The next step of this research is to test more formulations and choose the one which most efficiently targets the heart tissue. We will then assess whether delivery of mRNA to mice with ischemic hearts (resembling a heart attack) has any therapeutic effect.”
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Calculate Your Lifetime Risk of Heart Attack
Heart Risk Calculator assesses the lifetime risk for a heart attack and helps in making the right lifestyle choices to protect your heart.
Heart Risk Calculator assesses the lifetime risk for a heart attack and helps in making the right lifestyle choices to protect your heart.
COVID-19 Vaccine Corbevax Gets EUA for Kids Aged 5�12 Years
COVID-19 vaccine Corbevax has received a nod from the Drugs Controller General of India (DCGI) for emergency use authorization for the 5–12-year age group.
COVID-19 vaccine Corbevax has received a nod from the Drugs Controller General of India (DCGI) for emergency use authorization for the 5–12-year age group.
