Targeted therapy for treating certain cancers including glioblastoma, may also be beneficial in treating other neurologic diseases.
Targeted therapy for treating certaincancers including glioblastoma, may also be beneficial in treating other neurologic diseases. Over the past three decades, a number of significant pieces of work have been undertaken to estimate the prevalence of dementia at a European level, including:
‘Patients need enzyme replacement therapy to treat this condition, but a major limitation of FDA-approved enzyme replacement therapy is failure to cross the blood-brain barrier in the body.’
EURODEM study in the early 80s (updated in 2000)
Alzheimer Europe’s project European Collaboration on Dementia - EuroCoDe (2006-2008)
ALCOVE, the 1st EU Joint Action on Dementia (2011-2013).As the most recent of these studies is six years old, Alzheimer Europe recognised the importance of establishing more recent dementia prevalence estimates, using the most up-to-date academic literature on the subject.
The findings presented below are based on a collaborative analysis of prevalence studies published since the conclusion of the EuroCoDe project. A total of 16 studies meeting predefined quality criteria were included in the collaborative analysis.
For men, there has been a reduction in the prevalence of dementia across all age groups over the past ten years when compared to Alzheimer Europe’s 2008 EuroCoDe estimates.
For women, apart from the age group of women between 75 and 79 years, there has been a reduction in the prevalence of dementia over the past ten years when compared to EuroCoDe.
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Women continue to be disproportionately affected by dementia with 6,650,228 women and 3,130,449 men living with dementia in Europe.
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Alzheimer Europe’s Yearbook also highlighted significant limitations in the available research into dementia prevalence and a lack of research into:
the prevalence of younger people with dementia (i.e. those aged under 65) the prevalence of different types of dementia the number of people affected by different stages of dementia including mild cognitive impairment the prevalence of dementia of people from ethnic minority groups. Commenting on the findings, Alzheimer Europe Executive Director, Jean Georges, said:
"It is promising to see that healthier lifestyles, better education and improved control of cardiovascular risk factors seem to have contributed to a reduction of the prevalence of dementia.
However, our report also demonstrates that the number of people living with the condition is set to increase substantially in the years ahead, which will only place greater pressure on care and support services unless better ways of treating and preventing dementia are identified.
If people with dementia, their families and carers are to receive the high-quality and person-centred care they need, governments must ensure their health and care systems are ready to meet this demand and greater investments in research into the treatment and prevention of dementia are needed."
Source-Eurekalert