New study supports the mismatch hypothesis that claims that our bodies, which have evolved and adapted to digest the foods that our ancestors consumed, could struggle and mostly fail to metabolize a radically new set of foods.

‘The "mismatch hypothesis" claims that each of our bodies that have evolved and accustomed to digesting the foods that our ancestors ate could struggle and mostly fail to metabolize a radically new set of foods.
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"Humans evolved in a very different environment compared to the one we're currently living in," said Amanda Lea, the first author of the study. "No one diet is entirely bad. It's really about the mismatch between your evolutionary history and what you're currently consuming."




The "mismatch" approach has been around for years, but it's hard to test directly. To address this gap, the researchers collected interviews and biomarker data from individuals of Turkana ancestry who practice subsistence-level, nomadic pastoralism (the ancestral way of life for this group), and individuals who no longer practice pastoralism and live in urban areas.
The study found that Turkana, who moved to cities, exhibited poor cardiometabolic health, partly because of a shift toward "Western diets" high in refined carbohydrates. It also shows that being born in an urban area independently predicts adult health, such that life-long city dwellers will experience the greatest heart disease risk.
Source-Medindia