Diet Rich in Whole Grains May Offer Amazing Health Benefits

Eating a diet rich in whole grains may provide amazing health benefits. Discovery of the new compounds linked to whole grains may help us understand why whole grain products are good for our health.

New study sheds light on whole grain health benefits. Discovery of the new compounds associated with whole grains may significantly improve our knowledge and understanding of why whole grain products are good for our health.

Scientists //have discovered new compounds that may explain whole grain health benefits, reports a new study led by the University of Eastern Finland.

Eating Whole Grains Increases Metabolism And Calorie Loss
A diet rich in whole grains not only helps in improving digestion but also helps in increasing the resting metabolic rate, an effect that is similar to exercise.

‘Eating whole grain-rich diet may provide amazing health benefits. Discovery of the new compounds linked to whole grains may help us understand why whole grain products are good for our health.’
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A high intake of whole grains increased the levels of betaine compounds in the body which, in turn, was associated with improved glucose metabolism, among other things.

The findings shed new light on the cell level effects of a whole grain-rich diet and can help in the development of increasingly healthy food products.

"Whole grains are one of the healthiest foods there is. For instance, we know that a high intake of whole grains protects against type 2 diabetes and cardiovascular diseases. Up until now, however, we haven't understood the cellular mechanisms through which a whole grain-rich diet impacts our body," says Dr. Kati Hanhineva, Principal Investigator of the study at the University of Eastern Finland.

Intake of Whole Grains, Cereal Fibers Every Day may Reduce Risk of Premature Death
Such a diet reduces your risk of developing chronic diseases including cancer, heart disease, respiratory disease and diabetes.

Using metabolomics analysis, Dr. Hanhineva's research group investigated the effects of a whole grain-rich diet on the body's metabolites. The effects were studied in mice fed with bran-rich fodder, and in humans following a diet rich in whole grain products over the course of 12 weeks. A whole grain-rich diet increased the levels of betaine compounds in both mice and humans.

"This is the first time many of these betaine compounds were observed in the human body in the first place," Dr. Hanhineva says.

Whole Grains Can Lower The Risk of Colorectal Cancer
Whole grains which include brown rice, breads made from rye, barley, oats can reduce the risk of colorectal cancer.

At the end of the 12-week follow-up, the researchers also observed a correlation between improved glucose metabolism and increased presence of betaine compounds in the body.

"Pipecolic acid betaine, for example, is particularly interesting. Increased levels of pipecolic acid betaine after the consumption of whole grains was, among other things, associated with lower post-meal glucose levels."

How Much Whole Grain is Required to Reduce Type 2 Diabetes Risk?
Eating whole grains such as oats, wheat and rye can help prevent type 2 diabetes. Type of wholegrain product does not matter but how much a person consumes per day is important.

New Compound Worked Similarly to a Heart Drug in Cell Level Experiments

One of the betaine compounds discovered by the researchers is 5-aminovaleric acid betaine, 5-AVAB, which seems to cumulate in metabolically active tissues, such as the heart. With this observation in mind, the researchers set out to further test its effects in a cell model.

"We observed that 5-AVAB reduces cardiomyocytes' use of fatty acids as a source of energy by inhibiting the function of a certain cell membrane protein," Researcher Olli Kärkkäinen from the University of Eastern Finland says.

"This cell level effect is similar to that of certain drugs used for cardiovascular diseases. However, it is important to keep in mind that we haven't proceeded beyond cell level experiments yet. We need further research in animals and humans to verify that 5-AVAB really can impact the function of our body."

However, the discovery of the new compounds associated with whole grains significantly enhances our understanding of why whole grain products are good for our health.

"In the future, we seek to analyze in greater detail the multitude of effects these new compounds can have on the human body, and we will also look into how intestinal microbes possibly contribute to the formation of these compounds," Dr. Hanhineva continues.

Source-Eurekalert