Dietary acrylamide was not associated with an increased risk of lung cancer, according to data from a large prospective case-cohort study in the April 28 online issue of the Journal
Dietary acrylamide was not associated with an increased risk of lung cancer, according to data from a large prospective case-cohort study in the April 28 online issue of the Journal of the National Cancer Institute.
Acrylamide is formed in some starchy foods, such as potato chips and French fries, during high-temperature cooking. Epidemiological studies have found a positive association between dietary acrylamide intake and the risk of endometrial, ovarian, renal cell, and estrogen-receptor positive breast cancers.
Lung Cancer - Types, Causes, Symptoms, Diagnosis, Treatment and Prevention
Lung cancer is a malignant tumor in the lung tissues. Smoking is the main cause of lung cancer with symptoms like recurrent respiratory diseases.
Lung cancer is a malignant tumor in the lung tissues. Smoking is the main cause of lung cancer with symptoms like recurrent respiratory diseases.
After a follow-up of 13 years, 1,600 men and 295 women were diagnosed with lung cancer. When the investigators divided participants into five groups based on dietary acrylamide intake, they found no statistically significant difference in lung cancer incidence in men who consumed the highest and lowest amounts of acrylamide-containing foods. By contrast, the researchers found that women who ate the most acrylamide-containing foods had a statistically significant lower incidence of lung cancer compared with those in the group who consumed the least acrylamide-containing foods. All analyses were adjusted for smoking.
"Acrylamide intake was not associated with lung cancer risk in men but was inversely associated in women… This finding suggests that acrylamide is involved in human carcinogenesis through pathways other than genotoxicity," the authors write. They hypothesize that acrylamide may affect hormonal balances, which might explain how it could be associated with a reduction in lung cancer risk but an increase in risk of endometrial and ovarian malignancies.
Lung Biopsy - Indications - Procedures - Risks - FAQs - Reference
The procedure by which tissue samples are obtained from the lung is known as lung biopsy. The biopsy tissues obtained from the lungs are examined by a pathologist.
The procedure by which tissue samples are obtained from the lung is known as lung biopsy. The biopsy tissues obtained from the lungs are examined by a pathologist.
"In our view, speculation about the potential mechanisms of the protective effect of acrylamide on lung cancer among women should await confirmation of the association in additional studies," the editorialists conclude. "Perhaps the safer conclusion we can make from the Netherlands study is that the findings do not support a positive association between acrylamide intake from diet and risk of lung cancer."
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Acrylamide in Fried, Roasted or Grilled Food Doubles Cancer Risk in Women
A new study at the University of Maastricht has found that a common chemical called acrylamide caused by frying, roasting or grilling a food substance can double the risk of cancer in women.
A new study at the University of Maastricht has found that a common chemical called acrylamide caused by frying, roasting or grilling a food substance can double the risk of cancer in women.
Source-Eurekalert
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Nutritionists Warn Against Acrylamide
Acrylamide, the chemical compound that can cause cancer, present in french fries. Care must be taken to get around that, nutritionists say.
Acrylamide, the chemical compound that can cause cancer, present in french fries. Care must be taken to get around that, nutritionists say.
