Dopamine is a neurotransmitter that helps control the brain's reward and pleasure centers and helps regulate physical mobility and emotional response.
Mayo Clinic Researchers Extend Lifespan in Normal Mice
Senescent cells produce factors that damage adjacent cells and cause chronic inflammation, which is closely associated with frailty and age-related diseases.
Senescent cells produce factors that damage adjacent cells and cause chronic inflammation, which is closely associated with frailty and age-related diseases.
‘Dopamine D2 receptor (D2R) gene-environment interaction play an important role in longevity and aging.’
Dopamine is a neurotransmitter that helps control the brain's reward and pleasure centers and helps regulate physical mobility and emotional response. The researchers found that the dopamine D2 receptor gene (D2R) significantly influences lifespan, body weight and locomotor activity, but only when combined with an enriched environment that included social interaction, sensory and cognitive stimulation and, most critically, exercise. "The incorporation of exercise is an important component of an enriched environment and its benefits have been shown to be a powerful mediator of brain function and behavior," Thanos says.
The mice in the enriched environment lived anywhere from 16 to 22 percent longer than those in a deprived environment, depending on the level of D2R expression. "These results provide the first evidence of D2R gene-environment interaction playing an important role in longevity and aging," Thanos says.
Hormone, The Secret For Longevity Among The Rich
People with poor educational qualification have low levels of cortisol, which can lead to pain, depression, insomnia and heart palpitations.
People with poor educational qualification have low levels of cortisol, which can lead to pain, depression, insomnia and heart palpitations.
Research exploring this genetic-environmental interaction should lead to a better understanding and prediction of the potential benefits of specific environments, such as those including exercise, on longevity and health during aging.
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Brain Chemical Dopamine Plays a Role in Promoting Chronic Pain
By removing a collection of neurons called A11 that contain the brain chemical dopamine, scientists found that chronic pain was selectively diminished.
By removing a collection of neurons called A11 that contain the brain chemical dopamine, scientists found that chronic pain was selectively diminished.
Dopamine Brain Reward Molecule can Also Help in Learning to Avoid Unpleasant Experience
The brain chemical dopamine regulates how mice learn to avoid a disagreeable encounter, suggested a new research from the University of Pennsylvania.
The brain chemical dopamine regulates how mice learn to avoid a disagreeable encounter, suggested a new research from the University of Pennsylvania.
