Duloxetine, a drug approved in Canada, the US and Europe to treat major depression, is approved in Europe to treat stress urinary incontinence.
Urinary Incontinence - Symptom Evaluation
Urinary incontinence is loss of bladder control causing urine leakage. Severe urine leakage can happen when one coughs, sneezes, or during a sudden urge, where one is unable to visit the restroom in time.
Urinary incontinence is loss of bladder control causing urine leakage. Severe urine leakage can happen when one coughs, sneezes, or during a sudden urge, where one is unable to visit the restroom in time.
‘Though duloxetine reduces the frequency of incontinence, it has side effects such as violence and suicide attempts.’
The US Food and Drug Administration has noted a higher-than-expected rate of suicide attempts in open-label extensions of controlled trials of duloxetine for stress urinary incontinence. Researchers from the Nordic Cochrane Centre, Rigshospitalet, Copenhagen, Denmark, looked at clinical study reports from the European Medicines Agency to assess the benefits and harms of using this drug for stress urinary incontinence.
Although they found that duloxetine did lessen the frequency of incontinence, they also observed adverse effects associated with the drug. Harms potentially related to suicidality and violence were 4-5 times more common with duloxetine than with a placebo. "Given the uncertainty as to whether duloxetine leads to clinically significant improvement in quality of life ... we question the rationale for using duloxetine for stress urinary incontinence," writes Emma Maund, lead author and researcher at the Nordic Cochrane Centre, with coauthors.
Incontinence-Involuntary Loss of Urine - An impact on the daily life solution
Unintentional loss of urine has multiple implications to the sufferer. Urinary Incontinence has been noted to be a major barrier to social interests, entertainment, or physical recreation.
Unintentional loss of urine has multiple implications to the sufferer. Urinary Incontinence has been noted to be a major barrier to social interests, entertainment, or physical recreation.
Stress Incontinence About
Stress incontinence is the most common type of urinary incontinence. Women are more prone to it than men.
Stress incontinence is the most common type of urinary incontinence. Women are more prone to it than men.
Urodynamic Testing
What is urodynamic testing? When is it required? Find out what it is used for and if it is useful in the diagnosis of conditions responsible for urinary incontinence and urinary tract infections.
What is urodynamic testing? When is it required? Find out what it is used for and if it is useful in the diagnosis of conditions responsible for urinary incontinence and urinary tract infections.
