Electricalchemical Stimulation Helps Paralyzed Rats Learn to Walk Again

After a couple of weeks of neurorehabilitation with a combination of a robotic harness and electricalchemical stimulation, rats with severe spinal cord injury are learning to walk and run again.

Last June in the journal Science, Gregoire Courtine, of the Ecole Polytechnique Federale de Lausanne (EPFL), reported that rats in his lab are not only voluntarily initiating a walking gait, but they were sprinting, climbing up stairs, and avoiding obstacles.

Sixth Sense Rats
Lab rats acquired sixth sense after the implantation of microelectrodes in their brains.

Now, at the 2013 Annual Meeting of the American Association for the Advancement of Science (AAAS) in Boston, Courtine has described this research in detail and the next steps towards clinical trials to be done in Switzerland.

Courtine holds the International Paraplegic Foundation (IRP) Chair in Spinal Cord Repair at EPFL. At AAAS, in a symposium titled, "Engineering the Nervous System: Solutions to Restore Sight, Hearing, and Mobility," he outlines the range of neuroprosthetic technologies developed in his lab, which aim to restore voluntary control of locomotion after severe spinal cord injury.

He explains how he and his colleagues are interfacing the central nervous system with stretchable spinal electrode arrays controlled with smart stimulation algorithms - combined with novel robotic rehabilitation - and shows videos of completely paralyzed rats voluntarily moving after only weeks of treatment.

Drinking Problems in Rats Mirror Those Among Humans
Researchers have found that rats behave similarly to human alcohol abusers.

Courtine expects to begin clinical trials in human patients within the next two years.

At AAAS, he presents the 9 million euro European project NeuWalk, an effort dedicated to the transfer of technology from rats over to humans with spinal cord damage through development of effective neuroprosthetic systems for rehabilitation.

Alcohol Addiction Linked With Social Isolation During Adolescence Among Rats
Researchers have found that rats, which are socially isolated at a critical period of adolescence, are more likely to get addicted to amphetamine and alcohol.

The first phase of clinical studies will be conducted at the Lausanne University Hospital (CHUV), which has developed extensive expertise in the electrical-chemical stimulation of the human spinal cord.

The second phase will take place at the newly planned EPFL Valais Wallis academic cluster in Valais, Switzerland, to be inaugurated in 2015.

In Pakistan Hospital Rats Bite Twin Babies
Media reports said that newborn twins in a hospital in Pakistan's Rawalpindi city have been badly bitten by rats.

This health and biotechnology center in Valais will focus on new treatments and rehabilitation for people with physical disabilities.

This research program has the potential to develop effective treatment paradigms for rehabilitating individuals with severe spinal cord injury, for whom current rehabilitative treatments do not restore the ability to stand or walk.

Source-ANI