Even a Single Use of E-Cigarette can Diminish the Sensitivity of Cough Reflex

Nicotine was responsible for the effect on the cough reflex. Researchers suggested that nicotine had immediate stimulation of cough reflex and a delayed inhibition.

E-cigarette is a battery operated device designed to deliver nicotine with flavorings and other chemicals to users in vapor instead of smoke. Even a single use of an e-cigarette can diminish the sensitivity of cough reflex, revealed a study by the conducted by the American College of Chest Physicians.

The researchers tested 30 adult non-smokers with no history of asthma or respiratory diseases, and used cough tests to determine how e-cigarettes affect the cough reflex. Each study subject inhaled 30 puffs of an electronic cigarette, which contained nicotine in a vehicle of distilled water. After 15 minutes of the e-cigarette 'vaping' session, the subjects were tested again, using the Capsaicin cough challenge and then tested again after 24 hours.

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The results showed a significant decrease in cough reflex sensitivity among the subjects, as compared with their baseline levels. The authors observed that nicotine was probably responsible for the effect on the cough reflex and suggested that nicotine had an immediate stimulation of the cough reflex and a delayed inhibition.

The study is published in Journal Chest.

Source-ANI

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