Normal older adults who experience excessive sleepiness during the day or significant fatigue may have more brain atrophy than expected for their age.
Gene Variation Linked to Brain Atrophy in Mild Cognitive Impairment
Individuals diagnosed with mild cognitive impairment could experience accelerated rates of brain atrophy due to the presence of a gene variant, a new study found
Individuals diagnosed with mild cognitive impairment could experience accelerated rates of brain atrophy due to the presence of a gene variant, a new study found
‘Normal older adults who experience excessive sleepiness during the day or significant fatigue may have more brain atrophy than expected for their age.’
"Our results may help to identify individuals at higher susceptibility or risk for dementia prior to symptom onset so that appropriate interventions can be undertaken early to prevent progression to dementia," said lead author, Diego Z. Carvalho, a resident physician of neurology at the Mayo Clinic in Rochester, Minnesota. The research abstract was published recently in an online supplement of the journal Sleep and will be presented in Denver at SLEEP 2016, the 30th Anniversary Meeting of the Associated Professional Sleep Societies LLC (APSS).
In the Mayo Clinic Study of Aging, the authors identified 1,374 cognitively normal elderly aged 50 years and older who completed sleepiness and fatigue surveys and had a baseline structural magnetic resonance imaging (MRI). Excessive daytime sleepiness was defined as Epworth Sleepiness Scale of 10 or more. Fatigue severity was assessed with the Beck Depression Inventory-II.
Low Diastolic Blood Pressure Related With Brain Atrophy
In patients with arterial disease, low baseline diastolic blood pressure (DBP) appears to be associated with brain atrophy, whenever declining levels of blood pressure (BP) over time among patients who had a higher baseline BP were associated with less progression of atrophy.
In patients with arterial disease, low baseline diastolic blood pressure (DBP) appears to be associated with brain atrophy, whenever declining levels of blood pressure (BP) over time among patients who had a higher baseline BP were associated with less progression of atrophy.
Alzheimer's Risk Genes Linked to Brain Atrophy Identified
Two gene variations previously associated with Alzheimer's Disease are more specifically linked to brain atrophy, says study.
Two gene variations previously associated with Alzheimer's Disease are more specifically linked to brain atrophy, says study.
Cognitive Decline in Diabetes Associated With Brain Atrophy: Research
Cognitive decline in people with Type 2 Diabetes is likely due to brain atrophy, or shrinkage, that resembles patterns seen in the early stages of Alzheimer's disease, finds new research.
Cognitive decline in people with Type 2 Diabetes is likely due to brain atrophy, or shrinkage, that resembles patterns seen in the early stages of Alzheimer's disease, finds new research.
