More than 42% of the individuals reported a suicide attempt, and over 26% had misused drugs or alcohol to cope with transgender-related discrimination.
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Family Rejection may Increase Suicide Risk in Transgenders"
‘Family support and acceptance reduces the stress among transgenders which causes them to attempt suicide.’
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Overall, more than 42% of the individuals who self-identified as transgender or gender nonconforming reported a suicide attempt, and over 26% had misused drugs or alcohol to cope with transgender-related discrimination. The researchers report the increased risk of these health outcomes for individuals who experienced high or moderate levels of family rejection compared to little or no rejection. 
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"Gender minority stress and stigma contribute to the increased rates of depression, anxiety disorders, suicidality, and substance abuse in the transgender population. This study underscores the importance of family support and acceptance in mitigating that stress," says LGBT Health Editor-in-Chief William Byne, MD, PhD, Icahn School of Medicine at Mount Sinai.
Source-Eurekalert