Over 200,000 duloxetine bottles were recalled due to cancer-causing contaminants. FDA advises consulting doctors before stopping treatment.
![FDA Recalls Over 200,000 Duloxetine Bottles Over Cancer Risks FDA Recalls Over 200,000 Duloxetine Bottles Over Cancer Risks](https://images.medindia.net/health-images/1200_1000/tablet6.jpg)
‘Sudden withdrawal from #duloxetine can cause nausea, headaches, anxiety, and depression. #antidpressant #medindia’
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Nitrosamine Contamination in Duloxetine
It is the second-highest category of the FDA’s three recall classes and remains unclear how it got contaminated. The contamination could happen during manufacturing or storage.Advancements in technologies have led to the detection of even very small amounts of nitrosamine in multiple products. Nitrosamines are found in the environment, including water and certain foods.
Daily exposure to nitrosamine can not be avoided but it can be limited. According to the agency, taking a daily medication with nitrosamines at or below the acceptable daily intake limits for 70 years does not increase cancer risk.
Alternative Medications for Duloxetine
Duloxetine is a selective serotonin and norepinephrine reuptake inhibitors (SNRIs). SNRIs help increase levels of serotonin and norepinephrine in the brain Alternative medications like venlafaxine (Effexor) and desvenlafaxine (Pristiq) are also SNRIs that can be used as antidepressants.The FDA recommends to consult with a doctor before stopping the duloxetine treatment. Sudden withdrawal of the medication can cause nausea, anxiety, depression, pain, dizziness, nightmares, and headaches.
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Source-Medindia