First COVID-19 Patient Recovers Well After Administration of Plasma Therapy

First COVID-19 patient after receiving the Plasma Therapy at Max Hospital, Saket in Delhi has shown positive results with progressive improvement in his health condition and was recently weaned off the ventilator support. The 49-year-old man became the first patient to be administered plasma therapy at the Max Hospital (East Wing) here, the hospital said in a statement.

In convalescent plasma therapy, the antibodies of a person who has recovered from the virus are taken and transfused into a sick person (having the virus) to help boost the person’s immune system.

The patient from Delhi had tested positive for COVID-19 on April 4 and was admitted on the same day to the coronavirus facility at the Max Hospital with moderate symptoms and a history of fever and respiratory issues.

"His condition deteriorated during the next few days, and he soon required external oxygen to maintain saturation. He also developed pneumonia with Type I respiratory failure and had to be put on ventilator support on April 8," the hospital said.

When the patient showed no improvement, his family members requested the hospital to administer plasma therapy on compassionate grounds, a first of its kind treatment modality that is being used for the disease in India.

"The family came forward to arrange a donor for extracting plasma. The donor had recovered from the infection (confirmed by two consecutive negative reports) three weeks ago and again tested COVID-19 negative at the time of donation along with other standard tests to rule out infections like Hep B, Hep C, and HIV," the hospital said.

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The critically ill patient was administered fresh plasma as a treatment modality as a side-line to the standard treatment protocols on the night of April 14, it said.

"After receiving the treatment, the patient showed a progressive improvement, and by the fourth day, he was weaned off ventilator support on the morning of April 18 and continued on supplementary oxygen thereafter," it added.

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The hospital said the man had been shifted to a room with the round-the-clock monitoring facility.

"He has started taking oral feed since Sunday and is faring well," it said.

Speaking on the success of the first case administered under plasma therapy at the hospital, Sandeep Budhiraja, Group Medical Director, Max Healthcare, and Senior Director, Institute of Internal Medicine, said the case opened a new treatment opportunity during these challenging times.

"We are delighted that the therapy worked well in his case, opening a new treatment opportunity during these challenging times. But it is important that we also understand that plasma therapy is no magic bullet. During the patient’s treatment at the Max Hospital, other standard treatment protocols were followed, and we can say that plasma therapy could have worked as a catalyst in speeding up his recovery," Budhiraja said.

He also said the recovery could not be attributed 100 percent to the therapy.

"We cannot attribute 100 percent recovery to plasma therapy only, as there are multiple factors which carved his path to recovery," he said.

He further added that in a country like India, a therapy of such kind has a good potential to help COVID-19 patients who have disease severity, which fits into moderate to severe categories.

"Government regulations should work towards making it more accessible for hospitals across the country to be able to use it. One donor can donate 400 ml of plasma, which can save two lives, as 200 ml is sufficient to treat one patient," Budhiraja said.

So far, 47 people have lost their lives due to coronavirus in Delhi.

Source-IANS