The world's first whole exome sequence of small intestine neuroendocrine tumors has been completed by researchers at Mayo Clinic.
Carcinoid Tumors - Carcinoid Syndrome - Symptoms, Signs, Diagnosis & Treatment
Carcinoid tumors is a benign tumor that results in carcinoid syndrome. Only 8 to 10% of all carcinoid tumors are associated with the carcinoid syndrome.
Carcinoid tumors is a benign tumor that results in carcinoid syndrome. Only 8 to 10% of all carcinoid tumors are associated with the carcinoid syndrome.
"This is a very important step in achieving targeted therapies and individualized treatment approaches for patients with small bowel carcinoids," says Michaela Banck, M.D., a Mayo oncologist and lead author of a new study in the June edition of the Journal of Clinical Investigation. "Genomic analysis of the individual patient's tumors will help us identify new drugs that are targeted to the individual's disease."
The study revealed genomic alterations that might be susceptible to chemotherapy in the majority of patients (72 percent). Accordingly, an implied therapeutic road map for small intestine carcinoids might feature many related, but distinct, paths defined by individualized approaches and pharmacogenomics.
Epigenetics
In the recent years ‘epigenetics’ represents inheritable changes in gene expression that do not include DNA alterations.
In the recent years ‘epigenetics’ represents inheritable changes in gene expression that do not include DNA alterations.
The study was supported by grants from the Mayo Clinic Center for Individualized Medicine, Mayo Clinic, and The Richard M. Schulze Family Foundation.
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About Genetic Testing
Genetic testing helps to confirm a genetic condition in an individual and involves q complex laboratory techniques
Genetic testing helps to confirm a genetic condition in an individual and involves q complex laboratory techniques
About Mayo Clinic
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About the Center for Individualized Medicine
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Source-Newswise
