There is a relationship between binge or heavy alcohol drinking and DNA methylation and changes in POMC and PER2genes.
Bubbles and Brews - Alcohol Facts-Nutritive Value-Safe Intake-Effects-Famous Quotes
There is more to alcohol than mere intoxication. Infamous because of its social abuse but indispensable because of its many industrial applications.
There is more to alcohol than mere intoxication. Infamous because of its social abuse but indispensable because of its many industrial applications.
‘The researchers found that there was greater methylation of the DNA in the two genes, along with lower expression of the genes in the blood samples from the binge and heavy drinkers than those from the moderate drinkers. ’
Methylation is a change in the DNA that reduces gene expression. They measured changes in the methylation of two genes that have been implicated in the control of drinking behavior or the response to stress: the period 2 (PER2) and proopiomelanocortin (POMC) genes. Methylation changes were measured in blood samples drawn from groups of non-smokers who were moderate drinkers, binge drinkers, or heavy drinkers. These drinkers also participated in a laboratory study that measured behavioral alcohol motivation. During the three-day experiment, the participants experienced stress-related, neutral, or alcohol-related mental images on consecutive days. After this imagery, participants were exposed to alcoholic beer cues followed by an alcohol taste test to assess their motivation to drink. The expression of the PER2and POMC genes was measured in blood samples immediately after the behavioral experiments.
Greater PER2and POMCDNA methylation was associated with a greater subjective desire for alcohol immediately after presentation of the cues and after presentation of the alcoholic beer, and for alcohol consumed during the taste test.
Drug Detox – Alcohol, Opioid, Nicotine Detoxification
Drug detoxification (or drug detox) is a process that helps drug addicts to give up drugs with less or no withdrawal symptoms.
Drug detoxification (or drug detox) is a process that helps drug addicts to give up drugs with less or no withdrawal symptoms.
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Quiz on Alcohol
Alcohol consumption for recreation and relaxation has become a universal culture. But do you think you know enough about this drink – Take this quiz and find out.
Alcohol consumption for recreation and relaxation has become a universal culture. But do you think you know enough about this drink – Take this quiz and find out.
Alcohol Self Screening Test
Take this anonymous self-test to evaluate your alcohol consumption and determine if your drinking pattern poses a risk for hazardous health conditions.
Take this anonymous self-test to evaluate your alcohol consumption and determine if your drinking pattern poses a risk for hazardous health conditions.
