Grant has been awarded to explore the genetic variants that cause cerebral palsy. CB is a developmental brain disorder that impacts early motor development
What is Cerebral Palsy
Cerebral palsy is a developmental brain disorder that impacts early motor development, balance and posture. It affects 1 in 500 people and is the most common motor disability in childhood, according to the Centers for Disease Control and Prevention. As has been found in other similar brain disorders, a growing body of evidence suggests that a large proportion of CP cases are caused by rare variants in DNA. Dr. Moreno De Luca’s study will analyze DNA sequence data from Geisinger’s MyCode® Community Health Initiative paired with electronic health data, as well as DNA sequence data from GeneDx (Sema4), a leader in genomic testing and analysis for rare disorders, to identify the individual genes and regions of the genome responsible for CP.
Cerebral Palsy: Causes Symptoms Treatment Types Therapy and Communication Options
Cerebral palsy is a non-progressive motor neurological disorder that manifests during the early developmental stages of life.
Cerebral palsy is a non-progressive motor neurological disorder that manifests during the early developmental stages of life.
‘Birth asphyxia—a lack of oxygen to the brain before, during, or just after birth—was considered the most frequent cause of cerebral palsy for many years, but multiple studies have shown that it accounts for less than 10 percent of all cases.’
“We anticipate that this study will provide evidence to support the inclusion of genetic testing in routine clinical care for individuals with cerebral palsy,” Dr. Moreno De Luca said. “This project could also foster future research into molecular mechanisms of disease, helping to develop targeted therapies for specific genomic variants.” Dr. Moreno De Luca’s team will also analyze MRI studies of a subgroup of participants, allowing the team to identify shared neuroimaging features related to specific genes, gene families and molecular pathways.
Source-Eurekalert
Jigar Thakkar � an Ideal Example to Combat the Odds of Cerebral Palsy
Jigar Thakkar fights off the odds to bag the gold medal at the 21st national para-swimming championship.
Jigar Thakkar fights off the odds to bag the gold medal at the 21st national para-swimming championship.
Better Treatment Methods for Cerebral Palsy Children Revealed
Higher doses of constraint-induced movement therapy (CIMT) yield significant and lasting improvement in children with movement disorders, especially in everyday functional activities.
Higher doses of constraint-induced movement therapy (CIMT) yield significant and lasting improvement in children with movement disorders, especially in everyday functional activities.
Fracture Risk Increased in People With Cerebral Palsy
Specific subset of middle-aged men with cerebral palsy are shown to have up to 5.6 times more risk to suffer fractures than men without the disorder
Specific subset of middle-aged men with cerebral palsy are shown to have up to 5.6 times more risk to suffer fractures than men without the disorder
