Nicotine is known to cross the placenta and enter the fetal bloodstream and can lead to development problems in babies.

Nicotine is known to cross the placenta and enter the fetal bloodstream and can lead to development problems in babies. Therefore, blood tests to identify a nicotine marker called as cotinine was carried out among the mothers during first and second trimester of pregnancy.
The test results showed that 20% of mothers of schizophrenia patients had smoked heavily during pregnancy than 14.7 % of mothers of controls.
The study concluded that nicotine exposure during pregnancy increased babies risk of developing schizophrenia by 38%.
Senior researcher Professor Alan Brown, from the University of Columbia, New York, said, “To our knowledge, this is the first biomarker-based study to show a relationship between fetal nicotine exposure and schizophrenia.”
Source-Medindia