Gut can also Sense Bitter Tasting Food

The small intestine can also sense ‘sour’ toxins in food, and expel such items almost immediately.

The study claims that bitterness also slows the digestive process, keeping bad food in the stomach longer and increasing the chances that it will be expelled.

Typhoid and Paratyphoid Enteric Fevers?- Causes?
Typhoid and Paratyphoid Enteric Fevers are caused by bacteria called Salmonella typhi. Causes, symptoms, diagnosis and treatment of Typhoid and Paratyphoid Enteric Fevers are discussed.

The defense system in the gut against dietary toxins also triggers the production of a hormone that makes people feel full, presumably to keep them from eating more of the toxic food.

The finding may help scientists in devising improved therapies for ailments ranging from cancer to diabetes, and may also explain why certain isolated populations around the world have adapted to eat and enjoy local foods that taste bad to outsiders and make them sick.

Timothy Osborne, molecular biology and biochemistry professor and study senior author, claimed that the, performed with mice, and the results may also have implications in human.

Waterborne Disease
Interactive section of Medindia gives details regarding waterborne disease

"We have evolved mechanisms to combat the ingestion of toxins in our food. This provides a framework for an entirely new area of research on how our bodies respond to what is present in our diets," said Osborne.

Usually, mammals can detect bitter taste of toxins in food, particularly when they consume a lot of plant material, which tends to contain more bitter-tasting, potentially toxic ingredients than meat.

Cholera Epidemic Still Rampant in Guinea-Bissau, but Stable in Guinea
A cholera epidemic which has claimed 90 lives to-date in Guinea Bissau, with more than 3,900 people suffering from the disease, is spreading but no new cases have been reported from

When somebody swallows the toxins, bitter-taste receptors in the gut sense them and trigger the production of a hormone called cholecystokinin that both suppresses appetite and slows the movement of food from the stomach to the small intestine.

It was also found that cholesterol regulates the activity of bitter-taste receptors in the intestine, and diets high in plant material and potential toxins naturally are low in cholesterol, compared to low-toxin, high-cholesterol, meat-based diets.

Brit Children Afflicted by Vomiting, Panic Attack- Thanks to ?School Phobia?
An increasing number of Brit children are suffering from 'school phobia', warn experts. It has been estimated that one in every 20 children in England and Wales suffer from the

In small intestine cell cultures, low levels of cholesterol triggered a stronger receptor response, while high levels caused a weaker response.

The researchers saw the same response in mice that were given drugs to stop the production and absorption of cholesterol.

In fact, their receptors were not only more active, their small intestine cells produced two to three times the amount of the appetite-suppressing hormone in the presence of bitter food, compared to normal mice.

The scientist could utilise this knowledge to make medicines less bitter, which in turn would allow for increased palatability and quicker absorption.

The study has appeared in the latest issue of the Journal of Clinical Investigation.

Source-ANI
RAS/SK