Gut Flora Decides How a Body Reacts to High-Fat Diet

A new study has found that the composition of gut flora may be responsible for the different ways that people’s bodies react to high fat diet.

According to Remy Burcelin and Matteo Serino, researchers from the Inserm unit 1048 "Institute of Metabolic and cardiovascular diseases (I2MC)", the composition of the gut flora seems to determine the way in which the body develops certain metabolic disorders such as diabetes, regardless of any genetic modification, gender, age or specific diet. t is believed that nutritional additives such as gluco-oligosaccharides and dietary fibres that target the gut microbiota could prevent the development of metabolic disorders.

Low Calorie Diet | Low Calorie Foods
Low calorie meals or diet include foods that are high on nutritional content and yet have fewer calories. Updated information about low calorie diet or low calorie foods and its health benefits.

Gut flora is otherwise known as gut microbiota. There are roughly one thousand different species of bacteria that are nourished partly by what we eat.

Each person has their own specific gut flora and metabolism and these differ according to our dietary habits. Previous studies in mice have shown that a high-fat diet is capable of causing an imbalance in the gut flora, thus causing metabolic diseases such as diabetes or obesity.

Remy Burcelin's research spent three months studying how a fatty diet affected the gut flora of male mice of the same age, all with the same genetic background.

About Detox Diet
A detox diet helps remove harmful toxins from the body and can be followed for a day or a week. Detox diet includes fresh fruits, vegetables, juices, water.

Most of the mice developed diabetes while remaining thin, whereas some remained thin but did not develop diabetes.

In order to confirm the theory that gut flora affects the way in which our body reacts to a high-fat diet, the research team looked at the microbial profile of different types of mice (thin and diabetic and thin and non-diabetic, which indicates two phenotypes).

South Beach Diet - Basic Principles - Food Manuals - Drawbacks - FAQs
South Beach Diet plan originally developed to prevent heart disease, soon gained popularity as weight loss diet plan. This diet plan was developed by Dr.Arthur Agaston and Marie Almon.

They showed that there was a difference in the quantities of gut bacteria between diabetic and non-diabetic mice.

The thin but diabetic mice presented a flora composed mainly of "bacteroidetes" type bacteria, unlike the thin and non-diabetic mice that presented a flora composed mainly of "firmicutes" type bacteria.

Macrobiotic Diet - Yin and Yang Food - Advantages - Disadvantages - Theories
Macrobiotics is an Oriental theory that lays down guidelines for promoting well-being and longevity through systematic diet consisting mainly of whole grains and beans.

To find if is gut flora the cause or the result of metabolic disorders, Remy Burcelin's team directly modified the gut flora of a group of mice by adding dietary fibres and gluco-oligosaccharides to their high-fat diet.

"By adding these fibers, we modulated most of the physiological characteristics. The metabolism of the mice that we treated with these fibers was similar to that of the thin, non-diabetic mice. But the gut flora of the mice treated with fibers changed greatly compared to that of the other phenotypes observed", said Matteo Serino.

Source-ANI