The first randomized, double- blind, placebo-controlled trial assesses the efficacy of haloperidol as an adjunctive therapy for gastroparesis symptoms in the emergency department.

‘The addition of haloperidol to conventional therapy was better than conventional therapy alone for gastroparesis symptoms in the emergency department.
’

The study, by Roldan and colleagues, is the first randomized, double- blind, placebo-controlled trial to assess the efficacy of haloperidol as an adjunctive therapy for gastroparesis symptoms in the emergency department. The study found that compared with gastroparesis patients randomized to placebo, those who received Haloperidol had a statistically significant reduction of nausea and pain, with no side effects, suggesting that the addition of haloperidol to conventional therapy was better than conventional therapy alone. 




The study proposes that future research, with larger sample sizes, is needed to evaluate the external validity of the findings.
"A non-opiate treatment that actually works for gastroparesis exacerbations in the emergency department? Practice changing!" said John S. Garrett, MD, medical director of emergency management for Baylor Scott & White Health, Dallas, TX.
Source-Eurekalert