Testosterone is required for the recruitment of immune cells that can destroy tumor cells.
Highlights:
Why are females more likely to get adrenal gland cancer? Why are the outlooks for them worse?
- Hormone stimulation could be used to treat cancer
- The male hormone testosterone is necessary for the recruitment of macrophages, the immune cells that can eliminate tumor cells
Immune Cells that Destroy Tumor Cells
These inquiries are addressed by a scientific team under the direction of a CNRS researcher in a paper published in Science Advances. They show there is larger recruitment of immune cells called macrophages, which can destroy tumor cells, in male mice. Therefore, aggressive tumor progression is rarely observed in male mice, while macrophages do not inhibit the metastasis of tumors in female mice. The researchers discovered through molecular analysis that testosterone is required for the recruitment of macrophages that fight tumors.
Link Between Heart Defects from Birth and Adult Adrenal Cancer Found
Link between congenital cardiac malformation and adult adrenal cancer has been found by a research team who discovered a genetic mutation that explains why adults with severe congenital heart defects are at dramatically high risk for adrenal gland cancer.
Link between congenital cardiac malformation and adult adrenal cancer has been found by a research team who discovered a genetic mutation that explains why adults with severe congenital heart defects are at dramatically high risk for adrenal gland cancer.
‘The recruitment of immune cells capable of eliminating tumor cells depends on testosterone.’
Hormones to Treat Adrenal Cancer
Macrophages with the ability to eliminate tumor cells were mobilized to fight after the hormone was simply administered to females. Based on these results, the researchers conducted a second study using human data, which also found that men and women with adrenal cancer recruited macrophages at different rates. This finding raises the possibility that hormone stimulation could be used to treat this cancer, whose five-year survival rate is only 30%.Source-Medindia
Abnormalities in Tumor Cells Detected Easily by New Technique
Sensitive new assay finds abnormalities in tumor cells that other techniques may miss. The new assay detected 93 percent of gene fusions identified by currently available methods with no false positive errors.
Sensitive new assay finds abnormalities in tumor cells that other techniques may miss. The new assay detected 93 percent of gene fusions identified by currently available methods with no false positive errors.
How to Detect Circulating Tumor Cells
A researcher at Gold Coast’s Bond University suggests that opting for a psychological acupuncture could help reduce food cravings and lose weight.
A researcher at Gold Coast’s Bond University suggests that opting for a psychological acupuncture could help reduce food cravings and lose weight.
Self-perpetuating Signaling Circuit can Drive Tumor Cells to Spread
International researchers has identified a self-perpetuating signaling circuit inside connective tissue cells that allows these cells to form a front and a back and propelthemselves in a particular direction over a long period of time.
International researchers has identified a self-perpetuating signaling circuit inside connective tissue cells that allows these cells to form a front and a back and propelthemselves in a particular direction over a long period of time.
